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RESCUE"},{"term":"ANIMAL WELFATRE"},{"term":"AUSTRALIAN MADE WEEK"},{"term":"BEST OF"},{"term":"BLIND DOGS"},{"term":"BOXER"},{"term":"BRACHYCEPHALIC"},{"term":"CAMPLIFY"},{"term":"CANCELLED EVENTS"},{"term":"CANINE LYMPHONA"},{"term":"CHRISTMAS BOX"},{"term":"COBBER CHALLENGE"},{"term":"COST OF LIVING"},{"term":"DACHSHUND"},{"term":"DINGO"},{"term":"DOG ACTORS"},{"term":"DOG COSTUMES"},{"term":"DOG MOTION SICKNESS"},{"term":"DOG SUBSCRIPTION BOX"},{"term":"DOG WALKERS"},{"term":"EXHIBITION"},{"term":"FARM DOGS"},{"term":"FITPAWS"},{"term":"GENETICS"},{"term":"GIFT GUIDE"},{"term":"HEART DISEASE"},{"term":"HEARTWORM"},{"term":"HERO STORIES"},{"term":"HOMELESS"},{"term":"MELBOURNE"},{"term":"MOST POPULAR"},{"term":"MUSIC THERAPY"},{"term":"MUSICAL"},{"term":"NATIONAL LOST PET PREVENTION MONTH"},{"term":"OLD EVENTS"},{"term":"OLD REVIEWS"},{"term":"ORGANIC"},{"term":"PET BOARDING"},{"term":"PET EXPOS"},{"term":"PET MINDING"},{"term":"PET STROLLERS"},{"term":"PETS \u0026 PLANTS"},{"term":"PETSTOCK PAST EVENTS"},{"term":"REACTIVITY"},{"term":"REGULATIONS"},{"term":"REHABILITATION"},{"term":"RESCUE DOGS"},{"term":"SASH"},{"term":"SEEING EYE DOGS"},{"term":"STANDARDS"},{"term":"STORY DOGS"},{"term":"SURVEY"},{"term":"TELEHEALTH"},{"term":"TOILET TRAINING"},{"term":"TREATS"},{"term":"TRENDS"},{"term":"US APP"},{"term":"WET FOOD"},{"term":"WILLS"},{"term":"WORLD ANIMAL PROTECTION"}],"title":{"type":"text","$t":"Australian Dog Lover"},"subtitle":{"type":"html","$t":"Australian Dog Lover is the No.1 digital monthly magazine and website for dog lovers everywhere. We cover Dog Health, Dog Nutrition, Dog Behaviour; Dog Training Advice, Dog Events, the latest Dog Products and Services in Australia, Dog Product Reviews, Lifestyle, Gift Guides, Rescue Dog Stories, Dog Lovers Book Club etc."},"link":[{"rel":"http://schemas.google.com/g/2005#feed","type":"application/atom+xml","href":"https:\/\/www.australiandoglover.com\/feeds\/posts\/default"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/-\/PET+CANCER+AWARENESS+MONTH?alt=json-in-script\u0026max-results=6"},{"rel":"alternate","type":"text/html","href":"https:\/\/www.australiandoglover.com\/search\/label\/PET%20CANCER%20AWARENESS%20MONTH"},{"rel":"hub","href":"http://pubsubhubbub.appspot.com/"},{"rel":"next","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/-\/PET+CANCER+AWARENESS+MONTH\/-\/PET+CANCER+AWARENESS+MONTH?alt=json-in-script\u0026start-index=7\u0026max-results=6"}],"author":[{"name":{"$t":"Australian Dog Lover"},"uri":{"$t":"http:\/\/www.blogger.com\/profile\/00400760178634828393"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"generator":{"version":"7.00","uri":"http://www.blogger.com","$t":"Blogger"},"openSearch$totalResults":{"$t":"9"},"openSearch$startIndex":{"$t":"1"},"openSearch$itemsPerPage":{"$t":"6"},"entry":[{"id":{"$t":"tag:blogger.com,1999:blog-2020204049726645298.post-3636622954937851462"},"published":{"$t":"2023-10-28T12:33:00.005+11:00"},"updated":{"$t":"2023-10-29T11:21:39.275+11:00"},"category":[{"scheme":"http://www.blogger.com/atom/ns#","term":"CANCER"},{"scheme":"http://www.blogger.com/atom/ns#","term":"HEALTH AND WELLNESS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"ILLNESS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"PET CANCER AWARENESS MONTH"}],"title":{"type":"text","$t":"The Cancer Connection in Dogs and Humans"},"content":{"type":"html","$t":"\u003Cdiv\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhQ5bu9m98o_leS0Ak3iUd0Ju24AM6Q7wLzFTKYewl1j1PAKzQrrqsxEC3Dj8YH64_9cdiRpzQs7iATQzmMx29qs-shRrZXJ1t9LrjAyC0p98PRuyqZ1Bu0-EmQmeKapw-e51boDLQpH6DhM556lX5TOzCN8LI1i8cP8PQmLejhfxt_DJ2ceDTUuQiWgaI\/s1500\/Comparative_Oncology_Studies_Helping_Dogs_and_Humans_with_Cancer_Photo%20Cassiano%20Psomas%20via%20Unsplash.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1000\" data-original-width=\"1500\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhQ5bu9m98o_leS0Ak3iUd0Ju24AM6Q7wLzFTKYewl1j1PAKzQrrqsxEC3Dj8YH64_9cdiRpzQs7iATQzmMx29qs-shRrZXJ1t9LrjAyC0p98PRuyqZ1Bu0-EmQmeKapw-e51boDLQpH6DhM556lX5TOzCN8LI1i8cP8PQmLejhfxt_DJ2ceDTUuQiWgaI\/s16000\/Comparative_Oncology_Studies_Helping_Dogs_and_Humans_with_Cancer_Photo%20Cassiano%20Psomas%20via%20Unsplash.jpg\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cbr \/\u003E\u003Cb\u003E\u003Cbr \/\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003E\u003Cb\u003E\u003Cbr \/\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003E\u003Cb\u003EComparative Oncology: the cure is by our side...\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003EIt started with Harry, a seven-year-old Australian Cattle Dog, bounding into the clinic for his annual exam, and ended with dreadful news. Harry – a favourite and especially cheeky patient – had no history of ill health.\u0026nbsp;\u003C\/span\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjicoW1AQ1Q3IISqXscUplarY7_UNoHEN-f3-5ZrTMfjNx9GEBbMTunsbdYPoP_tDeUuEGYLigbPUJKTRVioq0zMOBmsofEAmys5Y9ADIUuGTDlG4rh0a3yvmkgrEvZG_Un7qbivfblJlryN8xjydHhQVP5tRwb8iOiySF3og3dVmXFjVYJ02BfdgiFcNw\/s526\/Comparative_Oncology_in_dogs_and_humans%20-%20Harry_the_Australian_Cattle_Dog_suffering_from_T-Cell_Lymphoma.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"403\" data-original-width=\"526\" height=\"245\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjicoW1AQ1Q3IISqXscUplarY7_UNoHEN-f3-5ZrTMfjNx9GEBbMTunsbdYPoP_tDeUuEGYLigbPUJKTRVioq0zMOBmsofEAmys5Y9ADIUuGTDlG4rh0a3yvmkgrEvZG_Un7qbivfblJlryN8xjydHhQVP5tRwb8iOiySF3og3dVmXFjVYJ02BfdgiFcNw\/s320\/Comparative_Oncology_in_dogs_and_humans%20-%20Harry_the_Australian_Cattle_Dog_suffering_from_T-Cell_Lymphoma.jpg\" width=\"320\" \/\u003E\u003C\/a\u003E\u003C\/div\u003EHowever, during his physical, all his superficial lymph nodes (or glands) were enlarged, and a quick look under the microscope was worrisome.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EReferral to an oncologist confirmed the worst: Harry had advanced multicentric \u003Ca href=\"https:\/\/hospital.cvm.ncsu.edu\/services\/small-animals\/cancer-oncology\/oncology\/canine-lymphoma\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003ET-cell lymphoma\u003C\/span\u003E\u003C\/a\u003E, and in his case, the prognosis was grave. Worse still, a family member had recently passed away from a similar cancer – an awful, tragic coincidence. \u003Cbr \/\u003E\u003Cbr \/\u003EIt turns out we share much more than our homes and hearts with our pets. Chances are, if you have lived with pets, or know someone who has, you will have been touched by animal cancer.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003ETragically, over a dog’s lifetime,\u0026nbsp;\u003Ca href=\"https:\/\/www.avma.org\/resources\/pet-owners\/petcare\/cancer-pets#:~:text=How%20common%20are%20neoplasia%20and,of%2010%20will%20develop%20cancer.\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003E1 in 4 will develop cancer\u003C\/span\u003E,\u003C\/a\u003E\u0026nbsp;and in dogs aged over 10, this increases to 1 in 2.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjOzw81ci5hrSX7UkAgVVEJUefyDVNKtB8F6XJo-uQ9EkK7NP2d0ktZopBMWY1WyjNfDCo-0din9LAHc-Lrz0uMob3Rvs2v-bumuAYC_PFhuis-LqhFJ-CeoC3lf9tLuOEk0Sllw-gtvf-4mJPnm_jVh-4tRtTDH3f9__JZ_TrxhzKf3BtxK6xtlH6_GVs\/s2048\/Compararive_Oncology_similarities_between_canine_cancers_and_human_cancers%20-%20senior%20dog%20with%20grey%20muzzle%20lying%20down%20on%20floor.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1365\" data-original-width=\"2048\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjOzw81ci5hrSX7UkAgVVEJUefyDVNKtB8F6XJo-uQ9EkK7NP2d0ktZopBMWY1WyjNfDCo-0din9LAHc-Lrz0uMob3Rvs2v-bumuAYC_PFhuis-LqhFJ-CeoC3lf9tLuOEk0Sllw-gtvf-4mJPnm_jVh-4tRtTDH3f9__JZ_TrxhzKf3BtxK6xtlH6_GVs\/s16000\/Compararive_Oncology_similarities_between_canine_cancers_and_human_cancers%20-%20senior%20dog%20with%20grey%20muzzle%20lying%20down%20on%20floor.jpg\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003EIn cats the numbers are similar: \u003C\/span\u003E\u003Ca href=\"https:\/\/www.csuanimalcancercenter.org\/2019\/11\/20\/common-cancers-in-cats\/\" rel=\"nofollow\" style=\"font-family: georgia;\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003E1 in 5 will develop cancer\u003C\/span\u003E\u003C\/a\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u0026nbsp;over their lifetime, jumping up to 1 in 3 in cats over 9 years of age. This may be an underestimate as cats are \u003C\/span\u003E\u003Ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5644631\/\" rel=\"nofollow\" style=\"font-family: georgia;\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eless likely to visit the vet\u003C\/span\u003E\u003C\/a\u003E\u003Cspan style=\"font-family: georgia;\"\u003E.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003EPet dogs and cats, and humans, develop cancer at the same rate, and in many cases, the cancers are just the same: they are diagnosed in the same way, treated with the same therapies, and share the same outcomes or prognoses. As just one example, dogs are the \u003Ca href=\"https:\/\/www.aaha.org\/your-pet\/pet-owner-education\/ask-aaha\/canine-cancer\/#:~:text=Lymphoma%20is%20one%20of%20the,any%20breed%20at%20any%20age.\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eonly non-human species\u003C\/span\u003E\u003C\/a\u003E that develop prostate cancer. \u003Ca href=\"https:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/1471-2407-13-403\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EPet cats\u003C\/span\u003E\u003C\/a\u003E and women both suffer the most treatment-resistant and deadly of all breast cancers, the triple negative form. \u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ca href=\"https:\/\/ccr.cancer.gov\/comparative-oncology-program\/about\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EComparative Oncology\u003C\/span\u003E\u003C\/a\u003E is an exciting field of research comparing cancer in humans and in our amazing companion animals, dogs and cats. By studying the remarkable similarities between humans and our pets – in the development, progression, and treatment of cancer – we gain insights that benefit all of us.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ci\u003ENote:\u003C\/i\u003E this research occurs in pets in the community, not in colonies of animals in the laboratory. \u003Cbr \/\u003E\u003Cbr \/\u003ECats and dogs are invaluable models for comparative oncology because they naturally develop cancer, including many of the same types found in humans: \u003Cb\u003Elymphoma\u003C\/b\u003E, like in Harry’s case; bone cancer (\u003Cb\u003Eosteosarcoma\u003C\/b\u003E); \u003Cb\u003Emelanoma\u003C\/b\u003E and other skin cancers; \u003Cb\u003Ebladder cancer\u003C\/b\u003E;\u003Cb\u003E head and neck\u003C\/b\u003E cancer; \u003Ca href=\"https:\/\/ccr.cancer.gov\/comparative-oncology-program\/comparative-brain-tumor-consortium\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ebrain\u003C\/span\u003E\u003C\/a\u003E and \u003Cb\u003Elung cancers\u003C\/b\u003E; \u003Cb\u003Eleukemias\u003C\/b\u003E and soft tissue \u003Cb\u003Esarcomas\u003C\/b\u003E; as well as less common cancers. \u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cb\u003ENon-Hodgkin's lymphoma \u003C\/b\u003E(NHL) is a cancer affecting the body's immune system. In humans, NHL is the seventh-most common type of cancer, affecting people of all ages.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EIn dogs, NHL is even more common, making up \u003Ca href=\"https:\/\/vcahospitals.com\/know-your-pet\/lymphoma-in-dogs#:~:text=Is%20lymphoma%20common%20in%20dogs,this%20has%20not%20been%20confirmed.\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003E20% of all canine cancers\u003C\/span\u003E\u003C\/a\u003E, mostly occurring in middle-aged dogs.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Ctable cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: left;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEiqXdYRgvRF0KjgvYS8_sFCdhNKySThdZEP2UG3oHAmB6rJeyGlkpYZJyZsdntT1dofW_-MYCqNYx8lyqDk1biZe0ZIayqZhphSxck5pxPdUgw0Fo5xk9gHCRKvyRMtHJ5ZbixygaAeX5v0CjEdQae09kN3tO4SwK3zwS8eQksjR5jYtC6FRpR9mk9FoZs\/s1920\/Colorado_State_University_newly_approved_lymphoma_medication_breakthrough_in_canine_cancer%20-%20Boxer%20receives%20injection.jpg\" style=\"clear: left; margin-bottom: 1em; margin-left: auto; margin-right: auto;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1080\" data-original-width=\"1920\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEiqXdYRgvRF0KjgvYS8_sFCdhNKySThdZEP2UG3oHAmB6rJeyGlkpYZJyZsdntT1dofW_-MYCqNYx8lyqDk1biZe0ZIayqZhphSxck5pxPdUgw0Fo5xk9gHCRKvyRMtHJ5ZbixygaAeX5v0CjEdQae09kN3tO4SwK3zwS8eQksjR5jYtC6FRpR9mk9FoZs\/s16000\/Colorado_State_University_newly_approved_lymphoma_medication_breakthrough_in_canine_cancer%20-%20Boxer%20receives%20injection.jpg\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Cspan style=\"background-color: white; color: #161616; text-align: start;\"\u003E\u003Ci\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003EA Boxer is being treated for cancer at a veterinary clinic in the USA\u003C\/span\u003E\u003C\/i\u003E\u003C\/span\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EThere may be a genetic susceptibility: it is most prevalent \u003Ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6090884\/\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ein breeds such\u003C\/span\u003E\u003C\/a\u003E as Golden Retrievers, Boxers, Bulldogs, Dobermann Pinschers, Rottweilers, Bernese Mountain Dogs, German Shepherds, Scottish Terriers, and Basset Hounds.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cb\u003ECanine NHL\u003C\/b\u003E originates within tissues of the immune system and can spread to different organs, including lymph nodes, liver, spleen, bone marrow, and the gastrointestinal tract.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ctable cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: right; margin-left: 1em; text-align: right;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgfb7X5ujqdQVnmypJV279axtZtOmdUIOzaxslQ1UBqTLImtwkGkUaxxKQRzqpLUE4aeCnLmz9nuN5cUTsmP_1qXZQvwyFrB1pJpAfEswcEngp7Yv7ylXKhM45b-LAgfU7NslKP0x4_lEamtdp4GbI1cvyYs9wZJbowwcDp9XgpSsYUC0WN_Sg7sYNzTNE\/s1080\/Comparative_Oncology_in_dogs_and_humans_risks_associated_with_exposure_to_environmental_pollutants_and_chemicals%20-%20Australian%20Cancer%20Foundation.jpg\" style=\"clear: left; margin-bottom: 1em; margin-left: auto; margin-right: auto;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1080\" data-original-width=\"1080\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgfb7X5ujqdQVnmypJV279axtZtOmdUIOzaxslQ1UBqTLImtwkGkUaxxKQRzqpLUE4aeCnLmz9nuN5cUTsmP_1qXZQvwyFrB1pJpAfEswcEngp7Yv7ylXKhM45b-LAgfU7NslKP0x4_lEamtdp4GbI1cvyYs9wZJbowwcDp9XgpSsYUC0WN_Sg7sYNzTNE\/w400-h400\/Comparative_Oncology_in_dogs_and_humans_risks_associated_with_exposure_to_environmental_pollutants_and_chemicals%20-%20Australian%20Cancer%20Foundation.jpg\" width=\"400\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Ci\u003ECredit: \u003Ca href=\"https:\/\/www.facebook.com\/AnimalCancerFoundation\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EAnimal Cancer Foundation (Facebook)\u003C\/span\u003E\u003C\/a\u003E\u003C\/i\u003E\u003C\/span\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003EThe causes of NHL in dogs are unclear, but may include genetic factors, ageing of the immune system, and exposure to \u003Ca href=\"https:\/\/cgejournal.biomedcentral.com\/articles\/10.1186\/s40575-022-00122-9\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ecertain environmental pollutants and chemicals\u003C\/span\u003E\u003C\/a\u003E. \u003Cbr \/\u003E\u003Cbr \/\u003ETreatment options for NHL in humans and dogs are \u003Ca href=\"https:\/\/www.upstate.edu\/whatsup\/2019\/0220-treatment-for-canine-cancer-serves-as-model-for-humans.php#:~:text=About%20canine%20lymphoma\u0026amp;text=%2D%2D%20Lymphoma%20is%20one%20of,for%20both%20dogs%20and%20people.\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Every similar\u003C\/span\u003E\u003C\/a\u003E but may vary in approach. In both cases, treatment typically involves a common chemotherapy protocol, and may be combined with radiation therapy or surgery.\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003ESome exciting new treatment options, such as targeted therapies and immunotherapies, are also being explored in \u003C\/span\u003E\u003Ca href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2021.621758\/full\" rel=\"nofollow\" style=\"font-family: georgia;\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eboth human and veterinary medicine\u003C\/span\u003E\u003C\/a\u003E\u003Cspan style=\"font-family: georgia;\"\u003E. Unfortunately, there are \u003C\/span\u003E\u003Ca href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2021.665784\/full#:~:text=precinctnetwork.org%5D.-,Monoclonal%20Antibodies,and%20effective%20for%20cancer%20therapy.\" rel=\"nofollow\" style=\"font-family: georgia;\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eno cancer immunotherapies\u003C\/span\u003E\u003C\/a\u003E\u003Cspan style=\"font-family: georgia;\"\u003E licensed for veterinary use, however research data are promising.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003EA range of clinical trials in canine lymphoma are recruiting patients (predominantly in the USA), and details can be found \u003Ca href=\"https:\/\/ebusiness.avma.org\/aahsd\/study_search_results.aspx\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ehere\u003C\/span\u003E\u003C\/a\u003E. As of June 2023, there are a couple of clinical trials actively recruiting canine lymphoma patients in some parts of Australia, and patients may be referred by their veterinarians, with details available \u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/10\/lifesaving-benefits-of-early-canine.html\" rel=\"\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ehere\u003C\/span\u003E\u003C\/a\u003E and \u003Ca href=\"https:\/\/www.uvths.com.au\/efficacy-trial-in-autologous-cancer-vaccine-for-dogs-diagnosed-with-lymphoma-treated-with-chemotherapy-or-palliative-care\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ehere\u003C\/span\u003E\u003C\/a\u003E. If you wish to find out more for your loved one, please discuss options with your veterinarian. \u003Cbr \/\u003E\u003Cbr \/\u003EI dread the days when an older large or giant breed dog comes to the clinic with pain or lameness, usually in a single front leg. In many cases, the diagnosis is terrible: \u003Cb\u003Eosteosarcoma \u003C\/b\u003E(OSA), or bone cancer, a brutally painful and aggressive cancer that has \u003Ca href=\"https:\/\/hospital.vetmed.wsu.edu\/2021\/05\/25\/canine-osteosarcoma\/#:~:text=Approximately%2090%2D95%25%20of%20dogs,are%20considered%20to%20be%20microscopic.\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Emetastasised to the lungs\u003C\/span\u003E\u003C\/a\u003E in 90-95% of dogs when they first show signs of swelling, lameness, and pain.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EThe cancer is relatively common in dogs, with \u003Ca href=\"https:\/\/www.intechopen.com\/chapters\/53932\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eover 10,000 cases\u003C\/span\u003E\u003C\/a\u003E diagnosed in the USA, per annum. This is likely an underestimate.\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003C\/span\u003E\u003Ctable align=\"center\" cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: left; margin-right: 1em; text-align: left;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgSSjwsqd31ZJ824nrdMv70pe1-Rc5oZlNU3zMSLJmbyPo_3rhAd90_bajB6f0WqNic9AtPSlut5vymJWj-Lwtcd9wgWSY39pPzzNdyOaxbXTRxpOy94ouAdSQM8NVXBucG7vbXGK6V-ZxBE4WkF1VTlz0RaRUWV_XM1qUQuOfd1WoNHlHu1xu4cFZ2mYA\/s1850\/Irish_Wolfhounds_are_one_the_dog_breeds_with_a_predisposition_to_Osteosarcoma%20%20-%20Dr%20Bec's%20dog%20Hilda%20upside%20down%20on%20her%20dog%20bed.jpg\" style=\"font-family: \u0026quot;Times New Roman\u0026quot;; font-size: medium; margin-left: auto; margin-right: auto; text-align: center;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1277\" data-original-width=\"1850\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgSSjwsqd31ZJ824nrdMv70pe1-Rc5oZlNU3zMSLJmbyPo_3rhAd90_bajB6f0WqNic9AtPSlut5vymJWj-Lwtcd9wgWSY39pPzzNdyOaxbXTRxpOy94ouAdSQM8NVXBucG7vbXGK6V-ZxBE4WkF1VTlz0RaRUWV_XM1qUQuOfd1WoNHlHu1xu4cFZ2mYA\/s16000\/Irish_Wolfhounds_are_one_the_dog_breeds_with_a_predisposition_to_Osteosarcoma%20%20-%20Dr%20Bec's%20dog%20Hilda%20upside%20down%20on%20her%20dog%20bed.jpg\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Ci\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003EDr Bec Vet's dog Hilda, the Irish Wolfhound\u003C\/span\u003E\u003C\/i\u003E\u0026nbsp;\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EThere appears to be a \u003Ca href=\"https:\/\/vcahospitals.com\/know-your-pet\/osteosarcoma-in-dogs\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Egenetic predisposition\u003C\/span\u003E\u003C\/a\u003E to OSA, as it predominantly affects Boxers, Irish Wolfhounds, Greyhounds, St. Bernards, Dobermanns, Rottweilers, German Shepherds, Great Danes, Golden Retrievers and Irish Setters. \u003Ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8683484\/\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EGentle giants\u003C\/span\u003E\u003C\/a\u003E are overrepresented, with most cases occurring in dogs over 40kg. \u003Cbr \/\u003E\u003Cbr \/\u003EThe cancer usually develops in the radius and ulna (above the wrist) or tibia and fibula (below the stifle or knee). Affected dogs may be painful, lame, lethargic, off their food, and may develop a dry cough. Other areas of the body can be affected, such as the toes, hip, or large bone of the hind leg (femur) but this is less common. Rarely, OSA can arise in the jaw, ribs, or other parts of the body. \u003Cbr \/\u003E\u003Cbr \/\u003EThe prognosis is terrible: dogs usually require amputation, and palliative care, such as strong pain relief and radiation therapy; most survive less than a year, usually only a \u003Ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1577656\/\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ehandful of months\u003C\/span\u003E\u003C\/a\u003E. Only 25% of dogs survive more than 2 years, and these cases involve aggressive surgical, radiation and chemotherapy interventions. Eighty percent (80%) of dogs with OSA die due to the \u003Ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4330401\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Esecondary tumours in the lungs\u003C\/span\u003E\u003C\/a\u003E. \u003Cbr \/\u003E\u003Cbr \/\u003EAlthough these statistics are grim, it’s not all bad news. There are numerous clinical trials studying new ways to diagnose OSA earlier, before it metastasises, and investigating new therapies. A silver lining in this dreadful disease is that such studies directly help humans with the same condition.\u003C\/span\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003EAlthough very rare, affecting fewer than \u003C\/span\u003E\u003Ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19197972\/\" rel=\"nofollow\" style=\"font-family: georgia;\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003E1000 humans\u003C\/span\u003E\u003C\/a\u003E\u003Cspan style=\"font-family: georgia;\"\u003E in the USA each year, osteosarcoma does develop in people, and almost always in children. OSA in dogs and children is nearly identical, and advances made in dogs have helped and \u003C\/span\u003E\u003Ca href=\"https:\/\/vet.osu.edu\/vmc\/cto\/owners\/curing-cancer-kids-and-dogs\" rel=\"nofollow\" style=\"font-family: georgia;\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eare continuing to help kids\u003C\/span\u003E\u003C\/a\u003E\u003Cspan style=\"font-family: georgia;\"\u003E. The ‘limb sparing’ surgeries, meaning a child can avoid amputation, \u003C\/span\u003E\u003Ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2599960\/\" rel=\"nofollow\" style=\"font-family: georgia;\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ewere developed\u003C\/span\u003E\u003C\/a\u003E\u003Cspan style=\"font-family: georgia;\"\u003E in none other than our wonderful canine friends with the very same disease.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjQS0e8gJ236vOthdS9YyjS87taQSJIi2sclBk-p9_-0SnXm-hu8hSlf-NqQ5v-lswpRMf_eFnqEZRFAYgIuAg-w08ETFjQi7MwMpGKfmE8K7QvM5RIiuamxE26I-QJY-sQXU0Piay2Hu5-axoKZ_cpWZBY92VxX_YQxYOndASfmh_TpG9yYT7GCQJu7ys\/s1095\/Comparative_Oncology_larger_dog_breeds_at_risk_of_osteosarcoma_Rottweiler_lying_down.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"729\" data-original-width=\"1095\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjQS0e8gJ236vOthdS9YyjS87taQSJIi2sclBk-p9_-0SnXm-hu8hSlf-NqQ5v-lswpRMf_eFnqEZRFAYgIuAg-w08ETFjQi7MwMpGKfmE8K7QvM5RIiuamxE26I-QJY-sQXU0Piay2Hu5-axoKZ_cpWZBY92VxX_YQxYOndASfmh_TpG9yYT7GCQJu7ys\/s16000\/Comparative_Oncology_larger_dog_breeds_at_risk_of_osteosarcoma_Rottweiler_lying_down.jpg\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003EA 2020 study identified common gene mutations in \u003Ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7564920\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EIrish Wolfhounds and Rottweilers\u003C\/span\u003E\u003C\/a\u003E, linked to developing OSA. Studies like this may help develop tests for earlier diagnosis of the disease in both dogs and people and provide new targets for cancer treatments. \u003Cbr \/\u003E\u003Cbr \/\u003EDogs may be enrolled in clinical trials for new therapies and these trials only offer potentially lifesaving new treatments for dogs with OSA and provide invaluable data on the safety and effectiveness of these treatments, which accelerates the process of making these treatments available for humans. Unlike many studies involving laboratory rodents, therapies that work in dogs with OSA are very likely to work in people. \u003Cbr \/\u003E\u003Cbr \/\u003EIn North America alone, over 80 clinical trials have studied new interventions for OSA, and 13 are \u003Ca href=\"https:\/\/ebusiness.avma.org\/aahsd\/study_search_results.aspx\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ecurrently recruiting\u003C\/span\u003E\u003C\/a\u003E. One fascinating \u003Ca href=\"https:\/\/ebusiness.avma.org\/aahsd\/study_search_results.aspx\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Estudy\u003C\/span\u003E\u003C\/a\u003E is investigating the link between \u003Cb\u003Edysbiosis\u003C\/b\u003E, or an \u003Cb\u003Eunbalanced gut microbiome\u003C\/b\u003E, and OSA in dogs. We know that intestinal dysbiosis is associated with \u003Ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6047065\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ecertain cancers in humans\u003C\/span\u003E\u003C\/a\u003E, and also whether or not patients will respond well to therapy. Perhaps the same applies in dogs. Again, if we find a link in our pets, we may have a new target for therapy, or option for intervention, to allow for earlier diagnosis and a better prognosis. \u003Cbr \/\u003E\u003Cbr \/\u003EThe \u003Ca href=\"https:\/\/vetmed.umn.edu\/departments\/centers-and-programs\/clinical-investigation-center\/current-clinical-trials\/coed-study\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EUniversity of Minnesota\u003C\/span\u003E\u003C\/a\u003E is recruiting healthy Irish Wolfhounds, and other large breeds, for a study to see if a simple blood test can detect OSA. This is funded by the\u0026nbsp;\u003Ca href=\"https:\/\/www.iwfoundation.org\/news\/coed-canine-osteosarcoma-early-detection-opens-for-enrollment-at-the-university-of-minnesota-website-08-22-2022\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EIrish Wolfhound Foundation\u003C\/span\u003E\u003C\/a\u003E, however, at this stage, only dogs living in the USA can be enrolled. Up to 20% of Wolfhounds will develop this heartbreaking illness. \u003Cbr \/\u003E\u003Cbr \/\u003EIf you have a Golden Retriever, Dane, Irish Setter, Wolfhound, Rotti or Leonberger and live in the USA, please contact the group \u003Ca href=\"https:\/\/vetmed.umn.edu\/departments\/centers-and-programs\/clinical-investigation-center\/current-clinical-trials\/coed-study\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ehere\u003C\/span\u003E\u003C\/a\u003E. For canine osteosarcoma, there are no active trials in Australia. \u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cb\u003EBladder cancer\u003C\/b\u003E in dogs \u003Ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24936033\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eshares many traits\u003C\/span\u003E\u003C\/a\u003E with bladder cancer in humans. This is a rarer cancer in dogs, though one we must be mindful of, and signs of this cancer include difficulty and pain when urinating, accidents in the house, blood in the urine, and persistent or recurring urinary tract infections. There are some fascinating USA trials looking at the effects of \u003Ca href=\"https:\/\/vet.osu.edu\/vmc\/cto\/clinical-trials\/temporarily-hold-probiome-canine-bladder-cancer\" rel=\"nofollow\" target=\"_blank\"\u003Eadding probiotics\u003C\/a\u003E, or orally administered ‘beneficial bacteria’ to standard treatments. \u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgxzB381o5tQrh1vMd8eeBPC-UcrWkF87Q-tbBYmLhIaTpXfiYtXY6n7rAWf82HK42KlXo-RZxRiKryoMafTA75aZLGmQqvKwXnXiWG2BS9FH182sOhAvnb-RZmKYNIUYbafxhzgWEq8eu7GoutwlommSX5eUnapnHPnDCavRYfadoTgGya-JX0RoZ9QhI\/s1199\/Comparative_Oncology_West_Highland_White_Terriers_one_of_the_dog_breeds_predisposed_to_bladder_Ccancer.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1199\" data-original-width=\"1199\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgxzB381o5tQrh1vMd8eeBPC-UcrWkF87Q-tbBYmLhIaTpXfiYtXY6n7rAWf82HK42KlXo-RZxRiKryoMafTA75aZLGmQqvKwXnXiWG2BS9FH182sOhAvnb-RZmKYNIUYbafxhzgWEq8eu7GoutwlommSX5eUnapnHPnDCavRYfadoTgGya-JX0RoZ9QhI\/w400-h400\/Comparative_Oncology_West_Highland_White_Terriers_one_of_the_dog_breeds_predisposed_to_bladder_Ccancer.jpg\" width=\"400\" \/\u003E\u003C\/a\u003E\u003C\/div\u003EThere is a \u003Ca href=\"https:\/\/www.thepetoncologist.com\/blog\/transitional-cell-carcinoma#:~:text=BRAF%20is%20a%20genetic%20mutation,been%20shed%20in%20the%20urine.\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Egenetic predisposition\u003C\/span\u003E\u003C\/a\u003E to bladder cancer, with Scottish terriers, West Highland White Terriers, Beagles, Australian Shepherds, Cattle Dogs, Jack Russell and Fox terriers and Bichon Frise breeds most commonly affected.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EA urine test that detects a common genetic mutation (a \u003Ci\u003EBRAF test\u003C\/i\u003E) can be used to diagnose bladder cancer in many cases, though the urine sample must be sent to the USA for testing. \u003Cbr \/\u003E\u003Cbr \/\u003EAmazingly, humans and dogs are the only species that spontaneously develop primary brain tumours.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhutYQ57xG3UgSMLtHyD0GOJjGwChObmb45eIZZ9_0IS-kxFH-hoX1tyJuVqC1GYaGhgu2hLqO26Stl3eUh_fWtqBdBuSp7nwYaLokCg1ltvwTlhGmH2QXdIRU2wuOgNwiCqhxKAX68bVlScQOrRki97v5SVYmwN0Kdfj5GFKLjxla5jNYNsRKzAsB-CYo\/s500\/The_Canine_Genome_percentage_of_genes_determining_physical_traits_in_Brachycephalic_dog_breeds.jpeg\" style=\"clear: right; float: right; margin-bottom: 1em; margin-left: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"358\" data-original-width=\"500\" height=\"286\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhutYQ57xG3UgSMLtHyD0GOJjGwChObmb45eIZZ9_0IS-kxFH-hoX1tyJuVqC1GYaGhgu2hLqO26Stl3eUh_fWtqBdBuSp7nwYaLokCg1ltvwTlhGmH2QXdIRU2wuOgNwiCqhxKAX68bVlScQOrRki97v5SVYmwN0Kdfj5GFKLjxla5jNYNsRKzAsB-CYo\/w400-h286\/The_Canine_Genome_percentage_of_genes_determining_physical_traits_in_Brachycephalic_dog_breeds.jpeg\" width=\"400\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003EIn dogs, around 35% of brain tumours are ‘\u003Ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29797768\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Egliomas\u003C\/span\u003E\u003C\/a\u003E’.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EEven with aggressive treatment, the prognosis for both dogs and humans with gliomas is terrible, and there are no cures. Shorter-faced (or brachycephalic) dogs such as English and French bulldogs, and Boxers, are more commonly affected than other breeds. \u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003ECurrently, we use surgery, chemotherapy, and radiation to extend lifespan and improve quality of life in both our pets and us.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgiYVvmrqL6yoPsgqgTFNGaJcnh8JRsgFnqhibgD6lhhY2B_xITzp9oHmqQKro3d-A8AbJAVcKZ-RSqCASY4BLB7hKZmOs98mVgAFmE3daAcCZp2RtmyAXgFESZDGv4udbg8KAwf8p5ohtPmHQKxP9r62pC0up-byW7zer04snvekxCPvCDS9O9ds_qZQk\/s804\/Study_of_Glioma_in_dogs_may_yield_insights_for_humans%20-%20Boxer%20profile.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"804\" data-original-width=\"750\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgiYVvmrqL6yoPsgqgTFNGaJcnh8JRsgFnqhibgD6lhhY2B_xITzp9oHmqQKro3d-A8AbJAVcKZ-RSqCASY4BLB7hKZmOs98mVgAFmE3daAcCZp2RtmyAXgFESZDGv4udbg8KAwf8p5ohtPmHQKxP9r62pC0up-byW7zer04snvekxCPvCDS9O9ds_qZQk\/w374-h400\/Study_of_Glioma_in_dogs_may_yield_insights_for_humans%20-%20Boxer%20profile.jpg\" width=\"374\" \/\u003E\u003C\/a\u003E\u003C\/div\u003EA \u003Ca href=\"https:\/\/research.vetmed.vt.edu\/clinical-trials\/current-studies\/molecular-combinatorial-therapy.html\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Etrial\u003C\/span\u003E\u003C\/a\u003E in Virginia, Maryland, is investigating the use of specially-targeted chemotherapy drugs, delivered directly to a dog’s brain tumour. The \u003Cb\u003E\u003Ci\u003EJohns Hopkins Hospital\u003C\/i\u003E\u003C\/b\u003E is trialling a \u003Ca href=\"https:\/\/www.hopkinsmedicine.org\/radiology\/provider-information\/vctn\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Enovel chemotherapy\u003C\/span\u003E\u003C\/a\u003E agent in canine brain tumours, and it is hoped that this will also help humans.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EIt is hoped that this \u003Ca href=\"https:\/\/www.if7cure.com\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Enew drug\u003C\/span\u003E\u003C\/a\u003E will target numerous types of cancer, and unlike many current chemotherapy drugs, this one can travel across the blood-brain barrier into the brain, and gain access to tumours. Data is promising in mice with \u003Ca href=\"https:\/\/www.nature.com\/articles\/s41416-020-01066-2\" rel=\"nofollow\" target=\"_blank\"\u003Ebrain tumours\u003C\/a\u003E, and the drug is now being tested in pet dogs with gliomas. \u003Cbr \/\u003E\u003Cbr \/\u003ELikewise, the dog is the one of the only species, apart from humans, to develop \u003Ca href=\"https:\/\/www.mdpi.com\/2227-9059\/11\/4\/1100\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eprostate cancer\u003C\/span\u003E\u003C\/a\u003E. Treatments are being \u003Ca href=\"https:\/\/www.hopkinsmedicine.org\/radiology\/provider-information\/vctn\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eco-developed\u003C\/span\u003E\u003C\/a\u003E in both dogs with this cancer, and humans. \u003Cbr \/\u003E\u003Cbr \/\u003EAnother breakthrough that may help people came with the development of a vaccine for melanoma in dogs. \u003Cb\u003ECanine melanoma\u003C\/b\u003E, especially oral melanoma, is highly aggressive and usually resistant to standard therapies. The vaccine, \u003Ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9693055\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Edeveloped initially for dogs\u003C\/span\u003E\u003C\/a\u003E, has paved the way for similar immunotherapy strategies in humans with melanoma. \u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ctable cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: right; margin-left: 1em; text-align: right;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhjmBJU91Gy3VQn-HufvacqxFsg58klYI1UF1b3U0SYvUWrOLvpJOBNggf2qOv9D99cTEdFnCIYJ-vsRSYVY9K4hGB7gCKoxD2AUhGGscnqH81jMOlouJ04TiE-ob2BF1VfvquTZD_-I_7wkcCI7HV1s4CBpUD9DNi2prfUh6Sfjv0TCZPeLo9hyLYYiwE\/s1080\/Canine_Cancer_Scottish_Terriers_at_risk_of_transitional_cell_carcinoma.jpg\" style=\"clear: left; margin-bottom: 1em; margin-left: auto; margin-right: auto;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1080\" data-original-width=\"1080\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhjmBJU91Gy3VQn-HufvacqxFsg58klYI1UF1b3U0SYvUWrOLvpJOBNggf2qOv9D99cTEdFnCIYJ-vsRSYVY9K4hGB7gCKoxD2AUhGGscnqH81jMOlouJ04TiE-ob2BF1VfvquTZD_-I_7wkcCI7HV1s4CBpUD9DNi2prfUh6Sfjv0TCZPeLo9hyLYYiwE\/w400-h400\/Canine_Cancer_Scottish_Terriers_at_risk_of_transitional_cell_carcinoma.jpg\" width=\"400\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Ci\u003E\u003Cspan style=\"font-size: medium;\"\u003EScottish Terriers have an increased risk of\u003Cbr \/\u003ETransitional Cell Carcinoma\u003C\/span\u003E\u003C\/i\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003EAdvances in genetics, including the \u003Cb\u003ECanine Cancer Genome Project\u003C\/b\u003E, through the \u003Ca href=\"https:\/\/acfoundation.org\/our-work\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EAnimal Cancer Foundation\u003C\/span\u003E\u003C\/a\u003E, aim to map the genes or DNA of cancers affecting different dog breeds, and may lead to better treatments for both dogs and humans.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003ETherapies may be tailored to the DNA of an individual pet's tumour, which is the same as ‘precision medicine’ in humans. This is not yet available in Australia, though is being used to make smarter treatment decisions for pet patients in the USA. \u003Cbr \/\u003E\u003Cbr \/\u003EOur dogs, and to a smaller degree, cats, are helping us understand the biology and treatment of both human and companion animal cancers. The \u003Ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6314649\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eremarkable similarities\u003C\/span\u003E\u003C\/a\u003E mean studying cancer in our pets can provide important information that fast tracks drugs to the clinic for both veterinary and human medicine.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EGiven their shorter lifespans, trials in our pets give us rapid insights: a drug that extends the life of a dog for 1 year may extend that of a person for 7, or longer. There is great hope for all of us affected by cancer … with the cure right by our side.\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cp class=\"MsoNormal\" style=\"font-family: \u0026quot;Times New Roman\u0026quot;; font-size: medium;\"\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003Ewritten by\u0026nbsp;\u003Cb\u003EDr Bec\u003C\/b\u003E, \u003Cb\u003EOctober\u0026nbsp;2023\u003C\/b\u003E\u0026nbsp;for\u0026nbsp;\u003Cb\u003E\u003Ci\u003EAustralian Dog Lover\u0026nbsp;\u003C\/i\u003E\u003C\/b\u003E(all rights reserved).\u003C\/span\u003E\u003C\/span\u003E\u003C\/p\u003E\u003Cp class=\"MsoNormal\" style=\"font-family: \u0026quot;Times New Roman\u0026quot;; font-size: medium;\"\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cu\u003E\u003Cb\u003EAbout our writer\u003C\/b\u003E\u003C\/u\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/p\u003E\u003Cp class=\"MsoNormal\" style=\"font-family: \u0026quot;Times New Roman\u0026quot;; font-size: medium;\"\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/p\u003E\u003Cp class=\"MsoNormal\" style=\"font-family: \u0026quot;Times New Roman\u0026quot;; font-size: medium;\"\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cspan\u003E\u003Cspan\u003E\u003Cb\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/p\u003E\u003Cdiv class=\"separator\" style=\"clear: both; font-size: x-large; text-align: center;\"\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cspan\u003E\u003Cspan\u003E\u003Cb\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEh6CjSGHCFac_2XLH56OxXrcJwXT681J23o_s66OCvyDjsXel_eITPxRr8SFvO-jezokhpyeuNuR_4FSGgwd9dPhwDM7w6X87cQ5qIPT745cFsxLMbiBUCekXTgfA0WtiYsvw7hwzygSeZ5kYXYPoMDoUMdq3OYJzu6p0v3lNXstRfgNE-o_kNsAH81YbA\/s1500\/Veterinarian_Rebecca_Wilcox_Dr_Bec_Vet_with_her_Irish_Wolfhound_Hilda.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1500\" data-original-width=\"1200\" height=\"320\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEh6CjSGHCFac_2XLH56OxXrcJwXT681J23o_s66OCvyDjsXel_eITPxRr8SFvO-jezokhpyeuNuR_4FSGgwd9dPhwDM7w6X87cQ5qIPT745cFsxLMbiBUCekXTgfA0WtiYsvw7hwzygSeZ5kYXYPoMDoUMdq3OYJzu6p0v3lNXstRfgNE-o_kNsAH81YbA\/s320\/Veterinarian_Rebecca_Wilcox_Dr_Bec_Vet_with_her_Irish_Wolfhound_Hilda.jpg\" width=\"256\" \/\u003E\u003C\/a\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cspan\u003E\u003Cspan\u003E\u003Cb\u003EDr Rebbecca Wilcox (Dr Bec)\u003C\/b\u003E is a Melbourne-based veterinarian and academic, working in the clinic, animal welfare, the media and medical research. She has a passion for sharing fascinating facts and the latest research on the intriguing lives and science of all animals, particularly those we share our lives with.\u003Cbr \/\u003E\u003Cbr \/\u003EDr Bec is a regular guest on Melbourne radio, a columnist for\u0026nbsp;\u003Cb\u003E\u003Ci\u003EAustralian Dog Lover Magazine\u003C\/i\u003E\u003C\/b\u003E,\u0026nbsp;\u003Cb\u003E\u003Ci\u003EAustralian Cat Lover Magazine\u003C\/i\u003E\u003C\/b\u003E, and\u0026nbsp;\u003Cb\u003E\u003Ci\u003EPet Insurance Australia\u003C\/i\u003E\u003C\/b\u003E, and she presents short segments on all things animal related (see\u0026nbsp;\u003Ca href=\"https:\/\/www.instagram.com\/drbecvet\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EInsta\u003C\/span\u003E\u003C\/a\u003E\u0026nbsp;and\u0026nbsp;\u003Ca href=\"https:\/\/www.facebook.com\/profile.php?id=100091573852713\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EFacebook\u003C\/span\u003E\u003C\/a\u003E). Her emphasis is on sharing of evidence-based veterinary advances and the empowerment of pet parents, and society, through promoting medical literacy, or the understanding of our pets’ health, and our own. She relishes reaching out to all animal loving audiences.\u003Cbr \/\u003E\u003Cbr \/\u003EHer academic and clinical research spans several areas, with a focus on the role of the microbiome in pet health, preventative medicine, developing new veterinary medicines, clinical trials that benefit animals and humans, and working to prevent antibiotic resistance.\u003Cbr \/\u003E\u003Cbr \/\u003EDr Bec advocates for animal charities that promote animal welfare, in Australia and overseas.\u003Cbr \/\u003EHer blog can be found at:\u0026nbsp;\u003Ca href=\"http:\/\/www.drbecvet.com\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cb\u003E\u003Cspan style=\"color: red;\"\u003Ewww.drbecvet.com\u003C\/span\u003E\u003C\/b\u003E\u003C\/a\u003E\u0026nbsp;and she may be contacted at\u0026nbsp;\u003Ca href=\"mailto:bec@drbecvet.com\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003E\u003Cb\u003Ebec@drbecvet.com\u003C\/b\u003E\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/span\u003E\u003Cspan style=\"font-size: large;\"\u003E\u0026nbsp;\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003E\u003Cb\u003ERelated Stories:\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/10\/lifesaving-benefits-of-early-canine.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EThe lifesaving benefits of early canine lymphoma diagnosis\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/08\/tummy-to-temperament-how-canine-gut.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003ETummy to temperament: how canine gut health affects behaviour\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E"},"link":[{"rel":"replies","type":"application/atom+xml","href":"https:\/\/www.australiandoglover.com\/feeds\/3636622954937851462\/comments\/default","title":"Post Comments"},{"rel":"replies","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/10\/the-cancer-connection-in-dogs-and-humans.html#comment-form","title":"0 Comments"},{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/3636622954937851462"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/3636622954937851462"},{"rel":"alternate","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/10\/the-cancer-connection-in-dogs-and-humans.html","title":"The Cancer Connection in Dogs and Humans"}],"author":[{"name":{"$t":"Australian Dog Lover"},"uri":{"$t":"http:\/\/www.blogger.com\/profile\/00400760178634828393"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"media$thumbnail":{"xmlns$media":"http://search.yahoo.com/mrss/","url":"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhQ5bu9m98o_leS0Ak3iUd0Ju24AM6Q7wLzFTKYewl1j1PAKzQrrqsxEC3Dj8YH64_9cdiRpzQs7iATQzmMx29qs-shRrZXJ1t9LrjAyC0p98PRuyqZ1Bu0-EmQmeKapw-e51boDLQpH6DhM556lX5TOzCN8LI1i8cP8PQmLejhfxt_DJ2ceDTUuQiWgaI\/s72-c\/Comparative_Oncology_Studies_Helping_Dogs_and_Humans_with_Cancer_Photo%20Cassiano%20Psomas%20via%20Unsplash.jpg","height":"72","width":"72"},"thr$total":{"$t":"0"}},{"id":{"$t":"tag:blogger.com,1999:blog-2020204049726645298.post-6996069591574164747"},"published":{"$t":"2023-10-27T11:56:00.012+11:00"},"updated":{"$t":"2023-10-30T16:55:56.798+11:00"},"category":[{"scheme":"http://www.blogger.com/atom/ns#","term":"CANCER"},{"scheme":"http://www.blogger.com/atom/ns#","term":"HEALTH AND WELLNESS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"ILLNESS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"NEWS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"PET CANCER AWARENESS MONTH"},{"scheme":"http://www.blogger.com/atom/ns#","term":"PREVENTION"}],"title":{"type":"text","$t":"Lifesaving Benefits of Early Canine Lymphoma Diagnosis"},"content":{"type":"html","$t":"\u003Cp\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhkmYK9-uKHCPGysDFs103KoXqssKroeBfPQw9YX5ZNUqcoKJjSMQfLioLGYbkop1AGjeteiRatZEHSdwQbmWYTRuvh7NqQkoI6imulvoyLh2khY35gKL0jsahoKH7jxbheRNkMqqojO34Jh3x0hQDYB5mvSiq0D8_EFdmc3T98rSjxU7Mjmqv8UjW14g8\/s1564\/Early_Diagnosis_of_Canine_Lymphoma_key_to_sucessful_treatment%20-%20Smiling%20German%20Shepherd%20lying%20on%20vet%20examination%20table.jpg\" style=\"clear: left; display: inline; float: left; margin-bottom: 1em; margin-right: 1em; text-align: center;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1080\" data-original-width=\"1564\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhkmYK9-uKHCPGysDFs103KoXqssKroeBfPQw9YX5ZNUqcoKJjSMQfLioLGYbkop1AGjeteiRatZEHSdwQbmWYTRuvh7NqQkoI6imulvoyLh2khY35gKL0jsahoKH7jxbheRNkMqqojO34Jh3x0hQDYB5mvSiq0D8_EFdmc3T98rSjxU7Mjmqv8UjW14g8\/s16000\/Early_Diagnosis_of_Canine_Lymphoma_key_to_sucessful_treatment%20-%20Smiling%20German%20Shepherd%20lying%20on%20vet%20examination%20table.jpg\" \/\u003E\u003C\/a\u003E\u003C\/p\u003E\u003Cbr \/\u003E\u003Cdiv class=\"separator\" style=\"clear: both;\"\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003E\u003Cb\u003EA Paw-sitive Path to Health\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv class=\"separator\" style=\"clear: both;\"\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv class=\"separator\" style=\"clear: both;\"\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“Did you know a quarter of dogs will develop cancer at some\u0026nbsp;\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003Epoint, and the risk increases to 50 per cent when they are over the age of 10 - according to the\u0026nbsp;\u003C\/span\u003E\u003Ca href=\"https:\/\/vetcancersociety.org\/\" rel=\"nofollow\" style=\"font-family: georgia;\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EVeterinary Cancer Society\u003C\/span\u003E\u003C\/a\u003E\u003Cspan style=\"font-family: georgia;\"\u003E?”\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u0026nbsp;explains\u0026nbsp;\u003C\/span\u003E\u003Cb style=\"font-family: georgia;\"\u003EKylie Baracz\u003C\/b\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u0026nbsp;who investigated for us the latest advances to combat canine lymphoma.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003EIt’s\u0026nbsp;\u003Cb\u003ENational Pet Cancer Awareness Month\u003C\/b\u003E\u0026nbsp;this November, and local biotech company\u0026nbsp;\u003Cb\u003E\u003Ci\u003EPharmAust Ltd\u003C\/i\u003E\u003C\/b\u003E\u0026nbsp;is calling for all dog owners to regularly\u0026nbsp;\u003Ca href=\"https:\/\/www.australiandoglover.com\/2022\/10\/treating-canine-lymphoma-why-you-should.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Einspect their dogs for any lumps and bumps\u003C\/span\u003E\u003C\/a\u003E\u0026nbsp;that seem out of the ordinary.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cb\u003ENovember 7th\u003C\/b\u003E\u0026nbsp;marks\u0026nbsp;\u003Cb\u003ENational Canine Lymphoma Awareness Day\u003C\/b\u003E, a day to highlight one of the most commonly diagnosed cancers in dogs! Lymphoma occurs in the white blood cells of the immune system. Symptoms can include tumours, lethargy, weight loss and loss of appetite.\u003Cbr \/\u003E\u003Cbr \/\u003E“The key to a good prognosis with canine lymphoma is early diagnosis, and this particular form of cancer is very rapidly progressive, so it’s important to act quickly,” said Dr Kim Agnew, principal investigator of\u0026nbsp;\u003Cb\u003E\u003Ci\u003EPharmAust\u003C\/i\u003E\u003C\/b\u003E’s anti-cancer drug trial for dogs with B-Cell lymphoma.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEibsdARm38baH5qb1QlmfRLwJxtSgWhj5PDeiNZ4T0m4gkQY6SUsu8amYuJjlMF9yAwYqynwQ05KW5amX1fpxHWbu0gjgfnK-f5ALe-N-Z9q8qtFzJFlD8_Z2l8cikWN429Vu-tXXrHypawldIR3qiz_ygG4G3BrP8phRSu3UT2pJEcVxanNGEc80LUXpA\/s1620\/Early_Diagnosis_of_Canine_Lymphoma_Veterinarian_conducts_health_check_for_lumps_and_bumps.jpg\" style=\"clear: left; font-family: \u0026quot;Times New Roman\u0026quot;; font-size: medium; margin-bottom: 1em; margin-right: 1em; text-align: center;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1080\" data-original-width=\"1620\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEibsdARm38baH5qb1QlmfRLwJxtSgWhj5PDeiNZ4T0m4gkQY6SUsu8amYuJjlMF9yAwYqynwQ05KW5amX1fpxHWbu0gjgfnK-f5ALe-N-Z9q8qtFzJFlD8_Z2l8cikWN429Vu-tXXrHypawldIR3qiz_ygG4G3BrP8phRSu3UT2pJEcVxanNGEc80LUXpA\/s16000\/Early_Diagnosis_of_Canine_Lymphoma_Veterinarian_conducts_health_check_for_lumps_and_bumps.jpg\" \/\u003E\u003C\/a\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EDr Agnew is leading a team of highly qualified veterinary oncologists in New South Wales, Queensland and Western Australia who are evaluating\u0026nbsp;\u003Cb\u003E\u003Ci\u003EPharmAust\u003C\/i\u003E\u003C\/b\u003E’s trial drug\u0026nbsp;\u003Cb\u003EMonepantel (MPL)\u0026nbsp;\u003C\/b\u003Ein dogs that have been newly diagnosed with B-Cell Lymphoma and have not started any treatment. The company also has trial centres in New Zealand and the United States evaluating the drug.\u003Cbr \/\u003E\u003Cbr \/\u003E“Monepantel is shown to be a safe and effective cancer treatment with an overall clinical benefit of 35 per cent and a median Time to Progression of 28 days,” explained Dr Agnew.\u003Cbr \/\u003E\u003Cbr \/\u003EOwners rated their dogs daily and recorded a Quality of Life (QoL) score between 1 (very poor) and 10 (normal) in the owner’s diary. The median QoL score for the 43 evaluable dogs across the entire study was high at eight. In the study, 74.4 per cent of dogs were rated more than out of 10.\u003Cbr \/\u003E\u003Cbr \/\u003EA presentation and a video providing further information about the Phase 2 veterinary clinical study and future directions can be found\u0026nbsp;\u003Ca href=\"https:\/\/vimeo.com\/871705472\/595fbb8200?share=copy\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ehere\u003C\/span\u003E\u003C\/a\u003E.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cb\u003E\u003Ci\u003EPharmAust\u003C\/i\u003E\u003C\/b\u003E\u0026nbsp;plans to use this data to open an Investigational New Animal Drug application with the\u0026nbsp;\u003Ci\u003EUnited States Food and Drug Administration’s Center for Veterinary Medicine\u003C\/i\u003E\u0026nbsp;and proceed with pivotal studies in 2024 to support product registration.\u003Cbr \/\u003E\u003Cbr \/\u003E“The use of MPL for canine lymphoma offers disease stabilisation combined with a canine and owner safety profile, which doesn’t exist currently in the therapeutic options,” says Dr Agnew.\u003Cbr \/\u003E\u003Cbr \/\u003E“I believe as we learn more about how to best manage canine lymphoma with MPL with ongoing studies, dogs and owners have an option to medicate their dogs at home safely. Most importantly, the family will see their pet manage their cancer with an excellent quality of life.”\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ctable cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: right; margin-left: 1em; text-align: right;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEh23CqZNrUeHVhMZIi4LFvrsBcY9fOA1k97Z5R6i1En7RlSg8qYCBghBZMBntbY1yYotJazp8s4xNORT4mviepkLiz2lH1P78pbHgt9hbPVZ3g1RzVr5xT5hRbGqGY-xdKFSyTKnsDuz1J4zTmJVWcBgWzW5WnwTif0l1p9T2hNJa9Dn3BT3p6JEWG64PI\/s1600\/Cavalier_King_Charles_Spaniel_Ruby_who_took_part_in_Monepantel_Canine_Lymphoma_cancer_treatment_trials.jpg\" style=\"clear: left; margin-bottom: 1em; margin-left: auto; margin-right: auto;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1600\" data-original-width=\"1200\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEh23CqZNrUeHVhMZIi4LFvrsBcY9fOA1k97Z5R6i1En7RlSg8qYCBghBZMBntbY1yYotJazp8s4xNORT4mviepkLiz2lH1P78pbHgt9hbPVZ3g1RzVr5xT5hRbGqGY-xdKFSyTKnsDuz1J4zTmJVWcBgWzW5WnwTif0l1p9T2hNJa9Dn3BT3p6JEWG64PI\/w300-h400\/Cavalier_King_Charles_Spaniel_Ruby_who_took_part_in_Monepantel_Canine_Lymphoma_cancer_treatment_trials.jpg\" width=\"300\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/www.pharmaust.com\/dt_testimonials\/ruby-from-brisbane\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe; font-size: medium;\"\u003ERuby from Brisbane - Testimonial\u003C\/span\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EVeterinary trial testimonies can be found\u0026nbsp;\u003Ca href=\"https:\/\/www.pharmaust.com\/veterinary-trial-testimonials\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ehere\u003C\/span\u003E\u003C\/a\u003E. Recruitment of dogs for trials with Monepantel has currently been paused.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cb\u003E\u003Ci\u003EPharmAust\u003C\/i\u003E\u003C\/b\u003E\u0026nbsp;Non-Executive Chairman Dr Roger Aston said Monepantel represents a new treatment approach for the management of B-Cell Lymphoma in dogs by “eliminating the need for chemotherapy and allowing dogs to maintain an excellent quality of life for an extended period of time”.\u003Cbr \/\u003E\u003Cbr \/\u003E“\u003Cb\u003EApproximately 80 per cent of dog owners decline treatment for various reasons\u003C\/b\u003E, including limited access to specialised veterinary oncologists and veterinary practices that can carry out chemotherapy,” he said.\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EFor instance, concerns over the dog’s quality of life due to the often-severe side effects that are a cornerstone of chemotherapy treatments, complying with the rigours of the chemotherapy regime once initiated, and major safety concerns for owners who handle and\/or are exposed to the chemotherapy while caring for their dog, and the high treatment costs.\u003Cbr \/\u003E\u003Cbr \/\u003E“MPL is available in tablet form, allowing dogs to be treated at home, without the side effects or safety concerns for owners,” said Dr Aston.\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Ctable cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: left;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEg7H7cp0e0t4IH9gdE2SV32VyVU1JRpIAmjNSIhI4pgq546Rfh55MeNX7I-wAp4mmlF9IHRwR_ORBttuEOtScaUhtBPXXubBUvNSI0PsDkLp9E5-fjsGX419eu7c2knfRYuy3l8seTrxYfJ7P3V6IuKpGhKMZVzrdqTGpwi1yIkQItYg8eH5iJEoryh3gQ\/s1650\/Treating_Canine_Lymphoma_Checking_Dogs_for_Lumps_PharmAust_Infographic_Common_Lymph_Nodes_Targeted_by_Lymphoma.png\" imageanchor=\"1\" style=\"clear: left; margin-bottom: 1em; margin-left: auto; margin-right: auto;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1162\" data-original-width=\"1650\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEg7H7cp0e0t4IH9gdE2SV32VyVU1JRpIAmjNSIhI4pgq546Rfh55MeNX7I-wAp4mmlF9IHRwR_ORBttuEOtScaUhtBPXXubBUvNSI0PsDkLp9E5-fjsGX419eu7c2knfRYuy3l8seTrxYfJ7P3V6IuKpGhKMZVzrdqTGpwi1yIkQItYg8eH5iJEoryh3gQ\/s16000\/Treating_Canine_Lymphoma_Checking_Dogs_for_Lumps_PharmAust_Infographic_Common_Lymph_Nodes_Targeted_by_Lymphoma.png\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Ci\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003ECommon lymph nodes targeted by canine lymphoma - Credit: \u003Cb\u003EPharmAust\u0026nbsp;\u003C\/b\u003E\u003C\/span\u003E\u003C\/i\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EFor more information about the trial, please visit\u0026nbsp;\u003Ca href=\"http:\/\/www.pharmaust.com\/petdogtrial\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cb\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ewww.pharmaust.com\/petdogtrial\u003C\/span\u003E\u003C\/b\u003E\u003C\/a\u003E\u003C\/span\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan\u003EWritten by\u0026nbsp;\u003C\/span\u003E\u003Cb\u003EKylie Baracz\u003C\/b\u003E\u003Cspan\u003E,\u0026nbsp;\u003Cb\u003EOctober\u003C\/b\u003E\u003C\/span\u003E\u003Cb\u003E\u0026nbsp;2023\u003C\/b\u003E\u003Cspan\u003E\u0026nbsp;for\u0026nbsp;\u003C\/span\u003E\u003Cb\u003E\u003Ci\u003EAustralian Dog Lover\u003C\/i\u003E\u003C\/b\u003E\u003Cspan\u003E\u0026nbsp;(all rights reserved).\u003C\/span\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cb\u003E\u003Cu\u003EAbout Kylie Baracz\u003C\/u\u003E\u003C\/b\u003E\u003Cbr \/\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhFa5SSqrKe9vsikielWjCsYXOOsaKAxfFdNtZx4EaO_EKyqCbaoNNB-JZi3b1u1xnBhS9JOFBay3vIOcxF-Q-TOluHVKv5Jm8Jdm2R-zLdLyakI6Bjrf8QiUEOiztQsa_UV6Dx29lKIGDia_bHv-3aKACyGhpBlmKj5_laBew3ABnUPbe6PxoqyKb-V6I\/s1500\/Content_by_Kylie_Writer_Kylie_Baracz_Biography_Pic.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1500\" data-original-width=\"1500\" height=\"320\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhFa5SSqrKe9vsikielWjCsYXOOsaKAxfFdNtZx4EaO_EKyqCbaoNNB-JZi3b1u1xnBhS9JOFBay3vIOcxF-Q-TOluHVKv5Jm8Jdm2R-zLdLyakI6Bjrf8QiUEOiztQsa_UV6Dx29lKIGDia_bHv-3aKACyGhpBlmKj5_laBew3ABnUPbe6PxoqyKb-V6I\/w320-h320\/Content_by_Kylie_Writer_Kylie_Baracz_Biography_Pic.jpg\" width=\"320\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003EKylie is a freelance writer, editor and content creator with over 13 years’ experience in the media industry.\u0026nbsp;\u003C\/div\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003EAs a former Dogs Life magazine editor, Kylie has a passion for writing for the pet industry and has worked with many pet brands including \u003Cb\u003EAPDTA\u003C\/b\u003E, \u003Cb\u003EPPGA\u003C\/b\u003E, \u003Cb\u003EPharmAust \u003C\/b\u003Eand \u003Cb\u003EAssistance Dogs Australia\u003C\/b\u003E.\u003C\/span\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003EYou can find her on Instagram\u0026nbsp;\u003Ca href=\"https:\/\/www.instagram.com\/contentbykylie\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003E@contentbykylie\u003C\/span\u003E\u003C\/a\u003E\u0026nbsp;or at\u0026nbsp;\u003Ca href=\"https:\/\/contentbykylie.com.au\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: red;\"\u003E\u003Cb\u003Econtentbykylie.com.au\u003C\/b\u003E\u003C\/span\u003E\u003C\/a\u003E\u0026nbsp;\u003Cbr \/\u003E\u003Cb\u003E\u003Cu\u003E\u003Cbr \/\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb style=\"font-family: georgia; font-size: large;\"\u003E\u003Cu\u003E\u003Cbr \/\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb\u003E\u003Cu\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb\u003E\u003Cu\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003EAbout PharmAust\u003C\/span\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cbr \/\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjePIbISF71qDOauxGEuauo48Oh-_z-26N4xVXqwHvFusvxBO4Ot3rMgzYLT25KE7hir6cvcTpkOZMfNWNvxVd8rSDotWxmtaWmlB0_nBEM7iHvQDLE3w8-ZV_QG9jB5Ms6DlzbaKdCa5Gau7sMDN38mQXQkm-00C3hQdErxCo48kEZOpEyUvnCpSZg\/s200\/PharmAust_Logo_Canine_Lymphoma_Monepantel_Dog_Cancer_Trials.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"53\" data-original-width=\"200\" height=\"85\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjePIbISF71qDOauxGEuauo48Oh-_z-26N4xVXqwHvFusvxBO4Ot3rMgzYLT25KE7hir6cvcTpkOZMfNWNvxVd8rSDotWxmtaWmlB0_nBEM7iHvQDLE3w8-ZV_QG9jB5Ms6DlzbaKdCa5Gau7sMDN38mQXQkm-00C3hQdErxCo48kEZOpEyUvnCpSZg\/w320-h85\/PharmAust_Logo_Canine_Lymphoma_Monepantel_Dog_Cancer_Trials.jpg\" width=\"320\" \/\u003E\u003C\/a\u003E\u003C\/div\u003EPAA is a clinical-stage company developing targeted cancer therapeutics for both humans and animals. The company specialises in repurposing marketed drugs lowering the risks and costs of development.\u003Cbr \/\u003E\u003Cbr \/\u003EPAA’s lead drug candidate is monepantel (MPL), a novel, potent and safe inhibitor of the mTOR pathway - a key driver of cancer. PAA is uniquely positioned to commercialise MPL for treatment of human and veterinary cancers as it advances the drug into Phase 2b clinical trial.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003ETo discover more, visit\u0026nbsp;\u003Ca href=\"https:\/\/www.pharmaust.com\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: red;\"\u003E\u003Cb\u003Ewww.pharmaust.com\u003C\/b\u003E\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003E\u003Cb\u003E\u003Cbr \/\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003E\u003Cb\u003ERelated Stories:\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2022\/10\/treating-canine-lymphoma-why-you-should.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003ETreating Canine Lymphoma: why you should check your dogs for lumps\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/10\/the-cancer-connection-in-dogs-and-humans.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EComparative Oncology: the cure is by our side\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2022\/11\/pet-cancer-awareness-and-palliative-care.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EPet Cancer Awareness and Palliative Care\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/07\/louie-beagle-has-lived-comfortably-with.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003ELouie the Beagle has lived comfortably with cancer for over a year\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/05\/managing-bellas-canine-lymphoma.html\" target=\"_blank\"\u003E\u003Cbr \/\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/05\/managing-bellas-canine-lymphoma.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EManaging Bella's Canine Lymphoma diagnosis\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E"},"link":[{"rel":"replies","type":"application/atom+xml","href":"https:\/\/www.australiandoglover.com\/feeds\/6996069591574164747\/comments\/default","title":"Post Comments"},{"rel":"replies","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/10\/lifesaving-benefits-of-early-canine.html#comment-form","title":"0 Comments"},{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/6996069591574164747"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/6996069591574164747"},{"rel":"alternate","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/10\/lifesaving-benefits-of-early-canine.html","title":"Lifesaving Benefits of Early Canine Lymphoma Diagnosis"}],"author":[{"name":{"$t":"Australian Dog Lover"},"uri":{"$t":"http:\/\/www.blogger.com\/profile\/00400760178634828393"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"media$thumbnail":{"xmlns$media":"http://search.yahoo.com/mrss/","url":"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhkmYK9-uKHCPGysDFs103KoXqssKroeBfPQw9YX5ZNUqcoKJjSMQfLioLGYbkop1AGjeteiRatZEHSdwQbmWYTRuvh7NqQkoI6imulvoyLh2khY35gKL0jsahoKH7jxbheRNkMqqojO34Jh3x0hQDYB5mvSiq0D8_EFdmc3T98rSjxU7Mjmqv8UjW14g8\/s72-c\/Early_Diagnosis_of_Canine_Lymphoma_key_to_sucessful_treatment%20-%20Smiling%20German%20Shepherd%20lying%20on%20vet%20examination%20table.jpg","height":"72","width":"72"},"thr$total":{"$t":"0"}},{"id":{"$t":"tag:blogger.com,1999:blog-2020204049726645298.post-5009124647674394998"},"published":{"$t":"2023-07-30T12:46:00.001+10:00"},"updated":{"$t":"2023-07-31T14:22:40.980+10:00"},"category":[{"scheme":"http://www.blogger.com/atom/ns#","term":"CANCER"},{"scheme":"http://www.blogger.com/atom/ns#","term":"HEALTH AND WELLNESS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"NEWS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"PET CANCER AWARENESS MONTH"},{"scheme":"http://www.blogger.com/atom/ns#","term":"VETERINARY"}],"title":{"type":"text","$t":"Vaccine trial for dogs with bone cancer at UQ"},"content":{"type":"html","$t":"\u003Cdiv\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhIu52vSTChbLQQNWJn2xK7PCd4YgOxWb-PZpHNfaHaliSdVMrAc0GvLWM5hZH7EA1uaSW8JaGvIub2K3Si3CkvHM0bhDOSbpXHpftDkggTKeUd-W4lkigmj2a2X7BZN54y2_-_nf43HzsLBh5tFWX8FXLTJVpY4HrotG6mm09GD8AjyGUyUWDhWnPKZB0\/s2000\/Vaccine_Trial_Australia_for_dogs_with_bone_cancer%20-%20old_Shepherd_Dog_receiving_vaccine_injection.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1333\" data-original-width=\"2000\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhIu52vSTChbLQQNWJn2xK7PCd4YgOxWb-PZpHNfaHaliSdVMrAc0GvLWM5hZH7EA1uaSW8JaGvIub2K3Si3CkvHM0bhDOSbpXHpftDkggTKeUd-W4lkigmj2a2X7BZN54y2_-_nf43HzsLBh5tFWX8FXLTJVpY4HrotG6mm09GD8AjyGUyUWDhWnPKZB0\/s16000\/Vaccine_Trial_Australia_for_dogs_with_bone_cancer%20-%20old_Shepherd_Dog_receiving_vaccine_injection.jpg\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cb\u003E\u003Ci\u003EUniversity of Queensland\u003C\/i\u003E\u003C\/b\u003E veterinary researchers are recruiting pet dogs diagnosed with cancer to test an experimental vaccine.\u003Cbr \/\u003E\u003Cbr \/\u003EThe clinical research trial is for dogs recently diagnosed with canine appendicular osteosarcoma, a common bone tumour that affects 10,000 dogs a year globally.\u003Cbr \/\u003E\u003Cbr \/\u003EDr Abhilasha Dadhich from UQ’s School of Veterinary Science said researchers will assess two vaccine formulations.\u003Cbr \/\u003E\u003Cbr \/\u003E“These treatments aim to stimulate a dog’s immune system to fight the spread of cancerous cells to other tissues of the body,” Dr Dadhich said.\u003Cbr \/\u003E\u003C\/span\u003E\u003Cblockquote\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E“We’re essentially ‘waking up’ the dog’s immune system to fight the cancer.\u003C\/span\u003E\u003Cspan style=\"font-family: georgia; font-size: x-large;\"\u003E”\u003C\/span\u003E\u003C\/blockquote\u003E\u003Cspan style=\"font-family: georgia; font-size: x-large;\"\u003E“\u003C\/span\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EThis has real potential to enhance the life expectancy of the pets in the trial.”\u003Cbr \/\u003E\u003Cbr \/\u003ETo be eligible, dogs need to have been diagnosed with \u003Cb\u003Eappendicular osteosarcoma of long bones of the limbs\u003C\/b\u003E with no evidence of metastasis, or cancer spread, based on a physical exam and radiographs.\u003Cbr \/\u003E\u003Cbr \/\u003EDogs can be any breed but must be proceeding to surgery to treat their cancer.\u003Cbr \/\u003E\u003Cbr \/\u003E“If the dog meets these parameters, their owner will simply need to sign an informed consent document after the trial has been explained,” Dr Dadhich said.\u003Cbr \/\u003E\u003Cbr \/\u003E“The veterinary clinic will then collect blood and cancerous bone tissue from the dog at the time of surgery.\u003Cbr \/\u003E\u003Cbr \/\u003E“Our prepared treatment is provided for free, administered to the dog in two doses. “The first vaccine dose will be given within two weeks of their surgery and the second dose as a booster three weeks later.\u003Cbr \/\u003E\u003Cbr \/\u003E“Further blood samples from the dog will be collected to assess its immune response.”\u003C\/span\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003Ctable cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: left;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhS3tc7ww4RxwivZP_hC0vifizswiI-2pflBxpAqsdEZ3BIakrzY5RwClFHmf3Tkz18vsm17sRy2rFwsU4Q1U7u5cG-v2XiJpkk7gTSEgLRZarpOGWctnrsV8XZ6zHI0aOrBg3k7wvKgDO9tf1H1gy3XpbD-yLxzwxdK9tQN7pc2lJUXxXtEE3B1ysiFDU\/s1280\/Greyhound%20Barney%20owned%20by%20Professor%20Allavena%20part%20of%20the%20bone%20cancer%20vaccine%20trial.jpg\" imageanchor=\"1\" style=\"clear: left; font-family: \u0026quot;Times New Roman\u0026quot;; font-size: medium; margin-bottom: 1em; margin-left: auto; margin-right: auto; text-align: center;\"\u003E\u003Cimg border=\"0\" data-original-height=\"720\" data-original-width=\"1280\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhS3tc7ww4RxwivZP_hC0vifizswiI-2pflBxpAqsdEZ3BIakrzY5RwClFHmf3Tkz18vsm17sRy2rFwsU4Q1U7u5cG-v2XiJpkk7gTSEgLRZarpOGWctnrsV8XZ6zHI0aOrBg3k7wvKgDO9tf1H1gy3XpbD-yLxzwxdK9tQN7pc2lJUXxXtEE3B1ysiFDU\/s16000\/Greyhound%20Barney%20owned%20by%20Professor%20Allavena%20part%20of%20the%20bone%20cancer%20vaccine%20trial.jpg\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Cspan style=\"background-color: white; color: #333333; text-align: start;\"\u003E\u003Ci\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003EBarney, owned by Professor Allavena, was given an early version of the vaccine when diagnosed \u003Cbr \/\u003Ewith an aggressive bone cancer\u0026nbsp;and 10 months later is alive and well.\u003C\/span\u003E\u003C\/i\u003E\u003C\/span\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EProfessor Rachel Allavena, who is leading the team conducting the trial, said it was hoped immune treatments would one day be a straightforward process for veterinarians around the world.\u003Cbr \/\u003E\u003Cbr \/\u003E“This technique has incredible potential to reduce suffering in our pets and eventually a variation may even be able to help humans,” Professor Allavena said.\u003Cbr \/\u003E\u003Cbr \/\u003E“We’re very eager to kick off this trial, as we have promising results from prior trials for dogs with cancer.”\u003Cbr \/\u003E\u003Cbr \/\u003EPet owners able to take their dog to the \u003Ca href=\"https:\/\/uqvets.com.au\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EUQ VETS Small Animal Hospital\u003C\/span\u003E\u003C\/a\u003E at Gatton for surgery and treatment will be preferentially selected, however the team would also like to recruit patients from elsewhere in Australia, except NSW (due to an ethics requirement).\u003Cbr \/\u003E\u003Cbr \/\u003EThe project team includes experienced veterinarians, board-certified pathologists and clinical trial experts who will provide regular monitoring and follow ups.\u003Cbr \/\u003E\u003Cbr \/\u003EApplications for the trial can be made via \u003Ca href=\"https:\/\/survey.app.uq.edu.au\/79E20EFE-DE3A-4652-8937-F992FA11EAE7\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: red;\"\u003E\u003Cb\u003Ethis webform\u003C\/b\u003E\u003C\/span\u003E\u003C\/a\u003E, or questions can be directed to Dr Dadhich \u003Ca href=\"mailto:a.dadhich@uq.edu.au\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ea.dadhich@uq.edu.au\u003C\/span\u003E\u003C\/a\u003E or Dr José Granados Soler \u003Ca href=\"mailto:j.granados@uq.edu.au\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ej.granados@uq.edu.au\u003C\/span\u003E\u003C\/a\u003E.\u003C\/span\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb style=\"font-family: georgia; font-size: large;\"\u003E\u003Ci\u003EMEDIA RELEASE, 21st July 2023\u003C\/i\u003E\u003C\/b\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E"},"link":[{"rel":"replies","type":"application/atom+xml","href":"https:\/\/www.australiandoglover.com\/feeds\/5009124647674394998\/comments\/default","title":"Post Comments"},{"rel":"replies","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/07\/vaccine-trial-for-dogs-with-bone-cancer.html#comment-form","title":"0 Comments"},{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/5009124647674394998"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/5009124647674394998"},{"rel":"alternate","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/07\/vaccine-trial-for-dogs-with-bone-cancer.html","title":"Vaccine trial for dogs with bone cancer at UQ"}],"author":[{"name":{"$t":"Australian Dog Lover"},"uri":{"$t":"http:\/\/www.blogger.com\/profile\/00400760178634828393"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"media$thumbnail":{"xmlns$media":"http://search.yahoo.com/mrss/","url":"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhIu52vSTChbLQQNWJn2xK7PCd4YgOxWb-PZpHNfaHaliSdVMrAc0GvLWM5hZH7EA1uaSW8JaGvIub2K3Si3CkvHM0bhDOSbpXHpftDkggTKeUd-W4lkigmj2a2X7BZN54y2_-_nf43HzsLBh5tFWX8FXLTJVpY4HrotG6mm09GD8AjyGUyUWDhWnPKZB0\/s72-c\/Vaccine_Trial_Australia_for_dogs_with_bone_cancer%20-%20old_Shepherd_Dog_receiving_vaccine_injection.jpg","height":"72","width":"72"},"thr$total":{"$t":"0"}},{"id":{"$t":"tag:blogger.com,1999:blog-2020204049726645298.post-6648619469487372125"},"published":{"$t":"2023-07-13T14:13:00.005+10:00"},"updated":{"$t":"2023-07-13T14:43:49.635+10:00"},"category":[{"scheme":"http://www.blogger.com/atom/ns#","term":"CANCER"},{"scheme":"http://www.blogger.com/atom/ns#","term":"CANINE LYMPHONA"},{"scheme":"http://www.blogger.com/atom/ns#","term":"ILLNESS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"PET CANCER AWARENESS MONTH"}],"title":{"type":"text","$t":"Louie the Beagle has lived comfortably with cancer for over a year"},"content":{"type":"html","$t":"\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhCLKH775u9awLoFTTLFOhjqJcLasrTRSIq06L8SZ2tLGwlddt1r7IudMPmqWFlOx81BZPKLIbhwfKBB9DWd6tGYfO3jZy9XIgfQ5iksoJDvvGowBAIvrUf9MpOsmLE4N8S6LpPui8AQZ3xlIedtRlILS8NnQk0mcMWqtTsTwyM62Ftwd-k1LMwBArm1lE\/s2016\/Louie_the_Beagle_surpasses_one_year_on_Monepantel_cancer_drug_from_PharmAust.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1512\" data-original-width=\"2016\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhCLKH775u9awLoFTTLFOhjqJcLasrTRSIq06L8SZ2tLGwlddt1r7IudMPmqWFlOx81BZPKLIbhwfKBB9DWd6tGYfO3jZy9XIgfQ5iksoJDvvGowBAIvrUf9MpOsmLE4N8S6LpPui8AQZ3xlIedtRlILS8NnQk0mcMWqtTsTwyM62Ftwd-k1LMwBArm1lE\/s16000\/Louie_the_Beagle_surpasses_one_year_on_Monepantel_cancer_drug_from_PharmAust.jpg\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cul style=\"text-align: left;\"\u003E\u003Cli\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E13-year old Beagle patient in canine trial surpasses 365 days with stable disease and continued excellent Quality of Life (QoL) \u003C\/span\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cul style=\"text-align: left;\"\u003E\u003Cli\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EMPL extends survival three-fold, to a median of 150 days, while maintaining quality of life.\u003C\/span\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cul style=\"text-align: left;\"\u003E\u003Cli\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EPharmAust’s commercial strategy aimed at bridging the options of standard-of- care with chemotherapy is on target \u003C\/span\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/span\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003E\u003Ci\u003E\u003Cbr \/\u003E\u003C\/i\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003E\u003Ci\u003EPharmAust Limited\u003C\/i\u003E\u003C\/b\u003E (\u003Ci\u003EASX: PAA \u0026amp; PAAO\u003C\/i\u003E), a clinical-stage biotechnology company, is pleased to announce a \u003Cb\u003Esignificant milestone for a patient\u003C\/b\u003E in the Phase 2 trial for the \u003Cb\u003Etreatment of canine B-cell Lymphoma\u003C\/b\u003E with \u003Ci\u003EMonepantel\u003C\/i\u003E (MPL). \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EB-cell Lymphoma in dogs has a poor prognosis. Unfortunately, without treatment, \u003Cb\u003Emany types of lymphoma are fatal within a few weeks\u003C\/b\u003E. In cases, the veterinarian may advise palliative care (steroid drugs) to reduce symptoms and possibly extend the survival time for a few weeks. However, even though chemotherapy can offer extended survival (typically around 12 months), it is only palliative and often results in an unacceptable adverse events profile and substantial costs. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003E\u003Ci\u003EPharmAust\u003C\/i\u003E\u003C\/b\u003E’s commercial strategy is to take the middle ground in the treatment of B-cell Lymphoma which is achieved by \u003Cb\u003Einducing stable disease for 4-6 months\u003C\/b\u003E with minimal side effects, so that the family and the dog can enjoy the limited time together. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EIn \u003Cb\u003E\u003Ci\u003EPharmAust\u003C\/i\u003E\u003C\/b\u003E’s current Phase 2 study, a 13-year-old Beagle “Louie”, has surpassed 365 days (one year) as a result of being treated solely with MPL, and showing no side effects while his Quality of Life (QoL) remains excellent. Louie was diagnosed with Progressive Disease (PD) at the end of his 28-day trial and despite this poor prognosis, \u003Cb\u003ELouie has achieved \u0026gt; 365 days of good quality of life\u003C\/b\u003E. Thus, it appears that dogs given MPL + prednisolone (or, in Louie’s case, MPL on its own) after the 28-day trial period are living three times longer than expected with good quality of life and no chemotherapy-related side effects. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjoHhMw1rltTshb3dDByrzKPmLNO5W1aLSIq1oCBXfXODfPaUNAW5UsEUHMHfcwGXd7Jum_P1R5TQcb-7kVEla57Uyl0_Ugue3RjEMAtvFSgrCg2pFqi1mmuNNrrX0niza814svUHb2u61FEQwqACm2avKZuc5nCHJgMX_7JBAuj8TvBYbqPXqqqBq9e_4\/s1600\/Louie_the_Beagle_in_the_car_living_over_one_year_thanks_to_Monepantel_cancer_drug_trial.jpg\" style=\"clear: right; float: right; margin-bottom: 1em; margin-left: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1600\" data-original-width=\"1200\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjoHhMw1rltTshb3dDByrzKPmLNO5W1aLSIq1oCBXfXODfPaUNAW5UsEUHMHfcwGXd7Jum_P1R5TQcb-7kVEla57Uyl0_Ugue3RjEMAtvFSgrCg2pFqi1mmuNNrrX0niza814svUHb2u61FEQwqACm2avKZuc5nCHJgMX_7JBAuj8TvBYbqPXqqqBq9e_4\/w300-h400\/Louie_the_Beagle_in_the_car_living_over_one_year_thanks_to_Monepantel_cancer_drug_trial.jpg\" width=\"300\" \/\u003E\u003C\/a\u003E\u003C\/div\u003ELouie’s owner Iain Gibson said Louie still enjoys his walks and “can still manage a decent pace” while sniffing everything in his path, \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“Mealtimes are Louie’s favourite part of the day and his second favourite thing is cuddles,” said Mr Gibson. “Louie also attends doggy day care two days a week and loves to chill out with his “pack” at home, quite happy doing nothing as long as he has someone to do nothing with.” \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThe Gibson family felt very fortunate the MPL trial was available at the time Louie became ill. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“The trial is 100% the best decision that we could have made for Louie. He deserved a break after the other issues with his knees and spleen he’s had over the years.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cblockquote\u003E“We’ve so enjoyed this extra time we’ve had with Louie and hoping that his eventual passing won’t be quite so painful as a result of this extra time,” said Mr Gibson. \u003C\/blockquote\u003E\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThe life expectancy of dogs with B-cell Lymphoma, treated with the standard of care (palliative steroid therapy) typically provides for 42-56 days of survival in association with progression. The combination of MPL with prednisolone has \u003Cb\u003Eextended median survival to these pet dogs of 150 days\u003C\/b\u003E. More importantly, owner surveys from dogs in the trial indicate an excellent QoL score feedback. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EMPL is already approved for veterinary use for a different indication in food-chain animals. \u003Cb\u003E\u003Ci\u003EPharmAust\u003C\/i\u003E\u003C\/b\u003E\u0026nbsp;is endeavouring to repurpose MPL as a safe and effective cancer treatment without the associated side effects of chemotherapy. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EPrincipal Investigator Dr Kim Agnew stated: “Despite Louie being with Progressive Disease at Day 28, the ongoing MPL therapy has helped to stabilise further development of the lymphoma since that time.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cblockquote\u003E“The tumour development slowed and, despite Louis still having evidence of lymphoma, his energy and quality of life remain excellent.” \u003C\/blockquote\u003E\u003C\/span\u003E\u003Cb\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana;\"\u003ETestimonial from Louie’s owner:\u003C\/span\u003E\u003C\/b\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003ELouie is a 13-year-old Beagle and has been a beloved family pet for over 10 years. He’s a very happy dog, loves people, other dogs and life in general. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgUI3Cwo2wkOtOPk4XRXddIl-IAq0XkabkuegM67vNqM2K7xm0wjtINLrqQvXdrMvvl0IJpg0m48QWJHTNHwhiXPLIEc2T7Uv0_WguuWpcgnUsaUALNeZu4GMn2VzhAMoV8g1TOjIJ-h_2FBr6IiRbmyJ8NBpwXzPfWTabLXP_UDlvOmexjSt9LnCio2_4\/s1600\/Louie_the_Beagle_surpasses_one_year_with_cancer_thanks_to_Monepantel_cancer_drug_trial.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1600\" data-original-width=\"1200\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgUI3Cwo2wkOtOPk4XRXddIl-IAq0XkabkuegM67vNqM2K7xm0wjtINLrqQvXdrMvvl0IJpg0m48QWJHTNHwhiXPLIEc2T7Uv0_WguuWpcgnUsaUALNeZu4GMn2VzhAMoV8g1TOjIJ-h_2FBr6IiRbmyJ8NBpwXzPfWTabLXP_UDlvOmexjSt9LnCio2_4\/w300-h400\/Louie_the_Beagle_surpasses_one_year_with_cancer_thanks_to_Monepantel_cancer_drug_trial.jpg\" width=\"300\" \/\u003E\u003C\/a\u003E\u003C\/div\u003EAfter Louie had been with us for a couple of years, he had knee issues and had to have both \u003Ca href=\"https:\/\/www.australiandoglover.com\/2017\/09\/cranial-cruciate-ligament-injury-in-dogs.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ecruciate ligaments operated on\u003C\/span\u003E\u003C\/a\u003E. When he was 9 years old, he got sick at Christmas time and ended up having a benign growth and his spleen removed. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EIn June 2022, we took him to see our local vet as we found some lumps in his neck. Louie was diagnosed with lymphoma and given 4-8 weeks to live. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EWe were given a couple of treatment options including chemotherapy or steroids. Chemo wasn’t an option for us, and we didn’t like the sound of the side effects of large doses of steroids. For one thing, making a Beagle even more hungry than usual would have been a challenge. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EOur vet told us about a drug trial that would possibly suit Louie if we were interested. An appointment was made to take Louie to \u003Ca href=\"https:\/\/www.facebook.com\/vsahospital\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EVeterinary Specialists Aotearoa\u003C\/span\u003E\u003C\/a\u003E (VSA) in Auckland for an initial assessment. At the end of the initial visit, we were given an initial prescription of Monepantel and an appointment for a follow up visit in 2 weeks. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003ELouie took the Monepantel tablets for those 2 weeks with no side effects and just carried on with the normal life of a 12-year-old Beagle. At the 2-week check-up, it was found that Louie’s lymph nodes had shrunk 20% and there were no side effects from the drug. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjU_8KLbiSt1t_92rSmpSCF_2bbC-D-T2m29szq3RuUe0DDr8_Ze803hQPB3ZrkjlClxcOfv9IzwI-kSFV1lnHR9T9bBYxSo6UEbTXW_OKtO8Cx71CuXK6xVrcj3MDZyYnxHUD7sdfEXNi6zPNnLJtmibL--kt0l38XBMZs4-yKzaQW_KJm20RWAIi-py0\/s1600\/Louie_the_Beagle_surpasses_one_year_on_the_Monepantel_cancer_drug_trial.jpg\" style=\"clear: right; float: right; margin-bottom: 1em; margin-left: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1600\" data-original-width=\"1200\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjU_8KLbiSt1t_92rSmpSCF_2bbC-D-T2m29szq3RuUe0DDr8_Ze803hQPB3ZrkjlClxcOfv9IzwI-kSFV1lnHR9T9bBYxSo6UEbTXW_OKtO8Cx71CuXK6xVrcj3MDZyYnxHUD7sdfEXNi6zPNnLJtmibL--kt0l38XBMZs4-yKzaQW_KJm20RWAIi-py0\/w300-h400\/Louie_the_Beagle_surpasses_one_year_on_the_Monepantel_cancer_drug_trial.jpg\" width=\"300\" \/\u003E\u003C\/a\u003E\u003C\/div\u003ELouie has had several follow up visits to VSA and at the last check-up, the size of his lymph nodes that can be easily measured have hardly changed since the 2-week measurements were taken. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003ELouie has continued taking the \u003Ci\u003EMonepantel\u003C\/i\u003E; we are now 12 months on from the initial diagnosis and Louie is still going strong. He’s still enjoying a good quality of life and fingers crossed he still has a little while left yet. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThe \u003Ci\u003EMonepantel\u003C\/i\u003E has been a great treatment for Louie as it has \u003Cb\u003Eextended his life well beyond the initial prognosis with no side-effects \u003C\/b\u003Eand has maintained his quality of life. -\u0026nbsp;Iain, New Zealand \u003C\/span\u003E\u003Cbr \/\u003E \u003Cbr \/\u003E\u003C\/span\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Ci\u003EThe Board authorises this announcement (Perth, 6 July 2023).\u003C\/i\u003E\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cb\u003E\u003Cu\u003EAbout PharmAust Limited: \u003C\/u\u003E\u003C\/b\u003E\u003Cbr \/\u003E\u003Cbr \/\u003EPharmAust Limited is listed on the Australian Securities Exchange (PAA) and the Frankfurt Stock Exchange (ECQ). PAA is a clinical-stage company developing therapeutics for both humans and animals. The company specialises in repurposing marketed drugs lowering the risks and costs of development. These efforts are supported by PAA’s subsidiary, Epichem, a highly successful contract medicinal chemistry company that generated $3.4 million in sales of goods \u0026amp; services in FY 2022. \u003Cbr \/\u003E\u003Cbr \/\u003EPAA’s lead drug candidate is monepantel (MPL), a novel, a potent and safe inhibitor of the mTOR pathway – a pathway having key influences in cancer growth and neurodegenerative diseases. MPL has been evaluated in Phase 1 clinical trials in humans and Phase 2 clinical trials in dogs. MPL treatment was well-tolerated in humans, demonstrating preliminary evidence of anticancer activity. MPL showed objective anticancer activity in dogs. PAA is uniquely positioned to commercialise MPL for treating human and veterinary cancers and neurodegenerative diseases as it advances a reformulated version of this drug through Phase 1 and 2 clinical trials.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan\u003E\u003Cb\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003ERelated Stories:\u003C\/span\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #2b00fe; font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/05\/managing-bellas-canine-lymphoma.html\" rel=\"\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EManaging Bella's Canine Lymphoma Diagnosis\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/05\/managing-bellas-canine-lymphoma.html\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe; font-size: large;\"\u003ETreating Canine Lymphoma: why you should check your dog for lumps\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E"},"link":[{"rel":"replies","type":"application/atom+xml","href":"https:\/\/www.australiandoglover.com\/feeds\/6648619469487372125\/comments\/default","title":"Post Comments"},{"rel":"replies","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/07\/louie-beagle-has-lived-comfortably-with.html#comment-form","title":"0 Comments"},{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/6648619469487372125"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/6648619469487372125"},{"rel":"alternate","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/07\/louie-beagle-has-lived-comfortably-with.html","title":"Louie the Beagle has lived comfortably with cancer for over a year"}],"author":[{"name":{"$t":"Australian Dog Lover"},"uri":{"$t":"http:\/\/www.blogger.com\/profile\/00400760178634828393"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"media$thumbnail":{"xmlns$media":"http://search.yahoo.com/mrss/","url":"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhCLKH775u9awLoFTTLFOhjqJcLasrTRSIq06L8SZ2tLGwlddt1r7IudMPmqWFlOx81BZPKLIbhwfKBB9DWd6tGYfO3jZy9XIgfQ5iksoJDvvGowBAIvrUf9MpOsmLE4N8S6LpPui8AQZ3xlIedtRlILS8NnQk0mcMWqtTsTwyM62Ftwd-k1LMwBArm1lE\/s72-c\/Louie_the_Beagle_surpasses_one_year_on_Monepantel_cancer_drug_from_PharmAust.jpg","height":"72","width":"72"},"thr$total":{"$t":"0"}},{"id":{"$t":"tag:blogger.com,1999:blog-2020204049726645298.post-2585899932210991813"},"published":{"$t":"2023-05-31T10:56:00.005+10:00"},"updated":{"$t":"2023-06-01T10:20:43.218+10:00"},"category":[{"scheme":"http://www.blogger.com/atom/ns#","term":"BOXER"},{"scheme":"http://www.blogger.com/atom/ns#","term":"ILLNESS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"PET CANCER AWARENESS MONTH"},{"scheme":"http://www.blogger.com/atom/ns#","term":"PREVENTION"},{"scheme":"http://www.blogger.com/atom/ns#","term":"VETERINARY"}],"title":{"type":"text","$t":"Cancer in Boxer Dogs identified as a health priority"},"content":{"type":"html","$t":"\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cb\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgHWIWmooTJupb6FraBCaT8rvL53TzXT-L7qyN7tx3qc2-WPNtCHgpK3k_776-HMpmxZLEn-2UBsLYTQk5JUo-R3Txg7dTPLqpYCa1ry83QyeVppPPRvo4K4PZOu0_3mYBZRrli_6YFy0XIzaN3-UXKNmkOE1I0zMKEarMH0kAvnA-z0K4q2lirvPpU\/s1850\/Cancer_in_Boxer_Dogs_health_priority_UK_Study_June_2023%20-%20Shelby%20Photo%20Credit%20Emily%20Stretch.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1229\" data-original-width=\"1850\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgHWIWmooTJupb6FraBCaT8rvL53TzXT-L7qyN7tx3qc2-WPNtCHgpK3k_776-HMpmxZLEn-2UBsLYTQk5JUo-R3Txg7dTPLqpYCa1ry83QyeVppPPRvo4K4PZOu0_3mYBZRrli_6YFy0XIzaN3-UXKNmkOE1I0zMKEarMH0kAvnA-z0K4q2lirvPpU\/s16000\/Cancer_in_Boxer_Dogs_health_priority_UK_Study_June_2023%20-%20Shelby%20Photo%20Credit%20Emily%20Stretch.jpg\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cbr \/\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cb\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana;\"\u003ENew RVC study identifies cancers as health priority in Boxer dogs\u003C\/span\u003E\u003C\/b\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EIn the largest ever study of Boxer dogs using veterinary records, researchers from the \u003Cb\u003E\u003Ci\u003ERoyal Veterinary College\u003C\/i\u003E\u003C\/b\u003E have identified the most common health disorders in the breed in the UK.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EResearch from the \u003Cb\u003E\u003Ci\u003ERoyal Veterinary College\u003C\/i\u003E\u003C\/b\u003E (RVC) has found the most common health conditions in UK Boxer dogs are \u003Cb\u003Eear problems\u003C\/b\u003E, \u003Cb\u003Etumours\u003C\/b\u003E and \u003Cb\u003Eeye ulcers\u003C\/b\u003E. These results will help owners and vets provide breed-focused targeted preventative healthcare and better inform and prepare potential owners for what to expect from the unique breed.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2018\/01\/evaluating-lumps-and-bumps-in-dogs.html\" rel=\"\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EThe Boxer dog\u003C\/span\u003E\u003C\/a\u003E has long been a popular dog breed in the UK, with this study finding that one in every 100 dogs in the UK are Boxers. Previous to this study, there were concerns that their relatively flattened faces (moderate brachycephaly) might mean Boxers were more likely to suffer from the problems commonly associated with flat face breeds such as breathing problems and skin fold infections. However, despite these concerns, until now, there has been limited evidence on the overall health status of Boxers.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThis study, led by the RVC’s \u003Ci\u003EVetCompass\u003C\/i\u003E programme, aimed to explore these and other important health concerns in Boxers. They did so via analysis of the clinical records of a \u003Cb\u003Erandom sample of 3,219 Boxer dogs\u003C\/b\u003E who received veterinary care in 2016.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EDisproving some false narratives about the breed’s health risks, the study found that many of the common disorders that Boxers experience are typical of all dog breeds, including ear infections, dental problems and obesity.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003ESo in that sense, \u003Cb\u003Emany of the health issues of Boxers are just typical dog problems overall\u003C\/b\u003E.\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EHowever, the study did identify some specific conditions that Boxers were at a substantially higher risk of developing. These included tumours\/cancers (\u003Ci\u003Eneoplasia\u003C\/i\u003E), gum mass (\u003Ci\u003Eepulis\u003C\/i\u003E) and eye ulceration. These show that the Boxer also has some important health concerns that are specific to the breed.\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThe study found that 14.2 per cent (one in seven) of Boxers were diagnosed with cancer (neoplasia) each year. \u003Cb\u003ECancer was also found to be the most common cause of death\u003C\/b\u003E (12.43% of all deaths), suggesting cancer should be considered a health priority for the breed.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003EFollowing neoplasia, the next most common causes of death identified were \u003Cb\u003Ebrain disorders\u003C\/b\u003E (9.54%) and \u003Cb\u003Emass lesions\u003C\/b\u003E (\u003Ca href=\"https:\/\/www.australiandoglover.com\/2018\/01\/evaluating-lumps-and-bumps-in-dogs.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Elumps\u003C\/span\u003E\u003C\/a\u003E) (8.38%). The most commonly reported overall groups of disorders alongside neoplasia, were skin disorders (17.74%) and ear disorders (10.41%).\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThe most commonly recorded specific disorders of Boxers included otitis externa (ear infection, being diagnosed in 7.15% of Boxers in 2016), epulis (fleshy lump on the gum) (5.84%); corneal ulceration (eye ulcer) (5.00%); \u003Ca href=\"https:\/\/www.australiandoglover.com\/2019\/07\/why-dog-dental-care-is-essential.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eperiodontal disease\u003C\/span\u003E\u003C\/a\u003E (gum disease) (4.63%); \u003Ca href=\"https:\/\/www.australiandoglover.com\/2019\/02\/heart-disease-in-dogs-causes-symptoms.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Eheart murmur\u003C\/span\u003E\u003C\/a\u003E (abnormal sound in heartbeat) (4.29%); and skin mass (abnormal skin growth\/lump) (4.29%).\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EBoxers were shown to be quite large dogs, \u003Cb\u003Eweighing on average 30.4kg\u003C\/b\u003E, which owners should take into account when considering acquiring a Boxer dog (e.g. cost of feeding, issues around handling). Female Boxers (27.6kg) on average weighed quite a bit less than males (33.0kg).\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Ctable cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: left;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEh8TmzmHrBmtvAdm76ikZKDJxJgNO9wjurOTrdsD6gYgMIFPRdeMQu_XzQRicOMJRJd5cxvYdKt7wTZdMGuKbhhCj13btd83O0tRe_tON9ThaeICKcrUhPI-3Y5GX6suUoBeGceA2yoa4O_law6vM7McYUMgYMpK0sMwsZ_vkYokE8R-qo9No5OkuQq\/s1850\/Cancer_in_Boxer_Dogs_identified_as_health_priority_UK_study_June_2023%20-%20Honey%20Photo%20Emily%20Stretch.jpg\" style=\"clear: left; margin-bottom: 1em; margin-left: auto; margin-right: auto;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1480\" data-original-width=\"1850\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEh8TmzmHrBmtvAdm76ikZKDJxJgNO9wjurOTrdsD6gYgMIFPRdeMQu_XzQRicOMJRJd5cxvYdKt7wTZdMGuKbhhCj13btd83O0tRe_tON9ThaeICKcrUhPI-3Y5GX6suUoBeGceA2yoa4O_law6vM7McYUMgYMpK0sMwsZ_vkYokE8R-qo9No5OkuQq\/s16000\/Cancer_in_Boxer_Dogs_identified_as_health_priority_UK_study_June_2023%20-%20Honey%20Photo%20Emily%20Stretch.jpg\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Ci\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003EHoney (Female Boxer, 7) - Credit Emily Stretch\u0026nbsp;\u003C\/span\u003E\u003C\/i\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EAdditional findings include:\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003EThe most common colours of Boxer dogs were brindle (23%) and dark red (23%) but 11% of Boxer dogs were white. Despite previous concerns, there was little evidence of major health differences between white and non-white Boxers.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003EAmong the 34 most common specific disorders, females had a higher risk of periodontal disease, skin masses, and urinary incontinence than males, while males had a higher probability of heart murmurs, aggression and aural (ear) discharge than females.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003EAmong the 22 most common groups of disorders, females were more likely to be diagnosed with mass lesions (lumps), dental disorders, and urinary system disorders, while males were more likely to be diagnosed with behavioural disorders.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003EWhite and non-white dogs did not differ in the risk for any of the 34 most common specific disorders.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;;\"\u003E✔️\u0026nbsp;\u003C\/span\u003EThe average lifespan of Boxer dogs overall was 10.46 years. There was no difference in the average lifespan of females (10.41 years) and males (10.53 years).\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThese results will assist veterinary surgeons to identify preventative health priorities for Boxers and provide prospective and current Boxer owners with information on health issues to look out for.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003EDan O’Neill\u003C\/b\u003E, Associate Professor in Companion Animal Epidemiology at the RVC, and lead author of the paper, said:\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“Boxer dogs are an iconic breed with a long and rich history. This study provides modern evidence to help owners to choose and care for their Boxer dogs today based on a solid scientific grounding that should ensure better lives for both the dogs and their owners.”\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003EAlison Skipper\u003C\/b\u003E, Researcher in Canine Health Research at the RVC, and co- author of the paper, said:\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“This study provides useful evidence that the Boxer, which is a moderately brachycephalic (flat-faced) breed, has fewer common health problems directly related to its body shape than the extreme brachycephalic breeds investigated by previous \u003Ci\u003EVetCompass \u003C\/i\u003Estudies. This both suggests that less extreme brachycephalic conformation has less impact on health and also shows how disease patterns may vary considerably between breeds, supporting the value of breed-specific health data.”\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003EBill Lambert\u003C\/b\u003E, Health, Welfare and Breeding Services Executive at The Kennel Club, added:\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“This widescale research, supported by the Kennel Club Charitable Trust, enables better understanding of breed-specific health concerns, and these findings will feed into the breed’s Health and Conservation Plans, managed by The Kennel Club to identify and monitor any concerns, and continue to improve health.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“We’re pleased this study indicates that most disorders faced by Boxers are fairly common for all dogs, and that there don’t seem to be any prevalent extreme health conditions, including those which can be associated with other Brachycephalic breeds. It remains \u003Cb\u003Ecrucial that puppy buyers do thorough research regarding breed health\u003C\/b\u003E and go to a responsible breeder; this plays an important part in improving the health and welfare of all breeds, now and in generations to come.”\u003C\/span\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cb\u003E\u003Cu\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003EReference:\u003C\/span\u003E\u003C\/u\u003E\u003C\/b\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan\u003EO’Neill et al. (2023) “Demography, common disorders and mortality of Boxer dogs under primary veterinary care in the UK”. Canine Medicine and Genetics.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan\u003EThe DOI for the paper is: 10.1186\/s40575-023-00129-w\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan\u003EThe full paper is available online at: \u003C\/span\u003E\u003Ca href=\"https:\/\/doi.org\/10.1186\/s40575-023-00129-w\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ehttps:\/\/doi.org\/10.1186\/s40575-023-00129-w\u003C\/span\u003E\u003C\/a\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan\u003E\u003Cb\u003E\u003Cu\u003EAbout the Royal Veterinary College\u003C\/u\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cspan\u003EThe Royal Veterinary College (RVC) is the UK's largest and longest established independent veterinary school and is a Member Institution of the University of London.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan\u003EIt is one of the few veterinary schools in the world that hold accreditations from the RCVS in the UK (with reciprocal recognition from the AVBC for Australasia, the VCI for Ireland and the SAVC for South Africa), the EAEVE in the EU, and the AVMA in the USA and Canada.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan\u003EThe RVC is ranked as the top veterinary school in the world in the QS World University Rankings by subject, 2023.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan\u003E·       The RVC offers undergraduate and postgraduate programmes in veterinary medicine, veterinary nursing and biological sciences.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan\u003E·       The RVC is a research-led institution, with 88% of its research rated as internationally excellent or world class in the Research Excellence Framework 2021.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan\u003E·       The RVC provides animal owners and the veterinary profession with access to expert veterinary care and advice through its teaching hospitals and first opinion practices in London and Hertfordshire.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cspan\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003EFor more information, head to\u0026nbsp;\u003Ca href=\"http:\/\/www.rvc.ac.uk\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cb\u003E\u003Cspan style=\"color: red;\"\u003Ehttp:\/\/www.rvc.ac.uk\u003C\/span\u003E\u003C\/b\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003E\u003Cb\u003ERelated Stories:\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #2b00fe; font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2015\/11\/boxer-breed-profile.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EBoxer Dog Breed Profile\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #2b00fe; font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2023\/01\/wsava-warns-of-emerging-crisis-caused.html\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EWSVA warns of emerging crisis caused by the popularity of Brachycephalic breeds\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2020\/08\/why-people-choose-flat-faced-dogs.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EWhy people choose flat-faced dogs despite major health risks\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E"},"link":[{"rel":"replies","type":"application/atom+xml","href":"https:\/\/www.australiandoglover.com\/feeds\/2585899932210991813\/comments\/default","title":"Post Comments"},{"rel":"replies","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/05\/cancer-in-boxer-dogs-identified-as.html#comment-form","title":"0 Comments"},{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/2585899932210991813"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/2585899932210991813"},{"rel":"alternate","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2023\/05\/cancer-in-boxer-dogs-identified-as.html","title":"Cancer in Boxer Dogs identified as a health priority"}],"author":[{"name":{"$t":"Australian Dog Lover"},"uri":{"$t":"http:\/\/www.blogger.com\/profile\/00400760178634828393"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"media$thumbnail":{"xmlns$media":"http://search.yahoo.com/mrss/","url":"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgHWIWmooTJupb6FraBCaT8rvL53TzXT-L7qyN7tx3qc2-WPNtCHgpK3k_776-HMpmxZLEn-2UBsLYTQk5JUo-R3Txg7dTPLqpYCa1ry83QyeVppPPRvo4K4PZOu0_3mYBZRrli_6YFy0XIzaN3-UXKNmkOE1I0zMKEarMH0kAvnA-z0K4q2lirvPpU\/s72-c\/Cancer_in_Boxer_Dogs_health_priority_UK_Study_June_2023%20-%20Shelby%20Photo%20Credit%20Emily%20Stretch.jpg","height":"72","width":"72"},"thr$total":{"$t":"0"}},{"id":{"$t":"tag:blogger.com,1999:blog-2020204049726645298.post-5735331694114771334"},"published":{"$t":"2022-10-28T12:33:00.014+11:00"},"updated":{"$t":"2023-10-27T11:23:52.977+11:00"},"category":[{"scheme":"http://www.blogger.com/atom/ns#","term":"CANCER"},{"scheme":"http://www.blogger.com/atom/ns#","term":"HEALTH"},{"scheme":"http://www.blogger.com/atom/ns#","term":"HEALTH AND WELLNESS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"ILLNESS"},{"scheme":"http://www.blogger.com/atom/ns#","term":"PET CANCER AWARENESS MONTH"},{"scheme":"http://www.blogger.com/atom/ns#","term":"WELLNESS"}],"title":{"type":"text","$t":"Treating Canine Lymphoma | Why you should check your dog for lumps"},"content":{"type":"html","$t":"\u003Cdiv\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjcVpKWEC_IfPzdBfJSwI8fvSS3JUrZRAa19c9bgTcdkbKsViUUL8kGunp0JwAQQJJCTJ5CQJdUKpN23wk28mW-ePZ3GDwIWDo5hv18WIrRbhWBXb-rpHHQQdW_ZYrelzS294zTDO-dO3W8BCrVzojaLDREWVbQrEZI5J3HoxD13TOrCu5MSp5IpUU2\/s1650\/Treating_Canine_Lymphoma_Vet_Checks_Lymph_Nodes_on_a_Terrier.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1102\" data-original-width=\"1650\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjcVpKWEC_IfPzdBfJSwI8fvSS3JUrZRAa19c9bgTcdkbKsViUUL8kGunp0JwAQQJJCTJ5CQJdUKpN23wk28mW-ePZ3GDwIWDo5hv18WIrRbhWBXb-rpHHQQdW_ZYrelzS294zTDO-dO3W8BCrVzojaLDREWVbQrEZI5J3HoxD13TOrCu5MSp5IpUU2\/s16000\/Treating_Canine_Lymphoma_Vet_Checks_Lymph_Nodes_on_a_Terrier.jpg\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003EWhen it comes to looking after our pets, their overall health is number one. But did you know that one in four dogs are diagnosed with canine cancer? \u003Cbr \/\u003E\u003Cbr \/\u003EAccording to the \u003Ca href=\"https:\/\/vetcancersociety.org\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EVet Cancer Society\u003C\/span\u003E\u003C\/a\u003E, close to \u003Cb\u003E50 percent of dogs over the age of 10 will develop some form of cancer\u003C\/b\u003E, which has sparked a campaign to get more owners checking for unusual lumps on their dog’s body at home. \u003Cbr \/\u003E\u003Cbr \/\u003EThese lumps, commonly found around the jaw and ‘knees’ of dogs can be a sign of enlarged lymph nodes, which is likely a sign of a common and aggressive canine cancer known as lymphoma. \u003Cbr \/\u003E\u003Cbr \/\u003E“Lymphoma is a cancer of one of the immune system cells,” says vet oncologist \u003Cb\u003EDr Jessica Finlay\u003C\/b\u003E from \u003Ca href=\"https:\/\/perthvetspecialists.com.au\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EPerth Vet Specialists\u003C\/span\u003E\u003C\/a\u003E in Western Australia.\u0026nbsp;\u003C\/span\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cblockquote style=\"font-family: georgia;\"\u003E“It is a body-wide disease affecting the lymph nodes or organs.” \u003C\/blockquote\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgzgwwbIWPW5xPULQ8_AmTYT76fk4H-7Zhk0CoW4urXK0lQRYbSV7PaNMhUkicff2mm9OtSVLlhGtaYZonQZGYRC3fg7M-ySs86L3wI9kQnG8RaTJw1_66y8ofw4AFkJZe6JH3R01eUBTBtZDTmYm_sDV-m4E38erw_BXy2L7jGKuegzT_6EHOBQ3c8\/s600\/Perth_Vet_Specialists_Veterinary_Oncologist_Dr_Jessica_Finlay.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"600\" data-original-width=\"600\" height=\"320\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgzgwwbIWPW5xPULQ8_AmTYT76fk4H-7Zhk0CoW4urXK0lQRYbSV7PaNMhUkicff2mm9OtSVLlhGtaYZonQZGYRC3fg7M-ySs86L3wI9kQnG8RaTJw1_66y8ofw4AFkJZe6JH3R01eUBTBtZDTmYm_sDV-m4E38erw_BXy2L7jGKuegzT_6EHOBQ3c8\/s320\/Perth_Vet_Specialists_Veterinary_Oncologist_Dr_Jessica_Finlay.jpg\" width=\"320\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThere are many\u0026nbsp;\u003C\/span\u003E\u003Cb style=\"font-family: georgia;\"\u003Edifferent types of lymphoma – at least 30 variations\u003C\/b\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u0026nbsp;– with most being high grade, meaning it will rapidly progress without treatment.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“The classifications [of lymphoma] are based on biological behaviour,” says Dr Finlay.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u0026nbsp;“The \u003C\/span\u003E\u003Cb style=\"font-family: georgia;\"\u003Eindolent types\u003C\/b\u003E\u003Cspan style=\"font-family: georgia;\"\u003E are slow to progress over months to years, whereas \u003C\/span\u003E\u003Cb style=\"font-family: georgia;\"\u003Ehigh grade types\u003C\/b\u003E\u003Cspan style=\"font-family: georgia;\"\u003E progress rapidly over weeks. It also depends on the type of lymphocytes (B cell and T cell) and anatomic location.”\u003C\/span\u003E\u003Cbr \/\u003E\u003Cb\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cb\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana;\"\u003EDiagnosing lymphoma \u003C\/span\u003E\u003C\/b\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EMany dogs with lymphoma will develop \u003Cb\u003Eenlarged lymph nodes\u003C\/b\u003E and, at the time the lumps are detected, most of the dogs will otherwise seem completely normal and well. Some dogs however will show varied symptoms such as lethargy, vomiting, diarrhoea, or weight loss or \u003Cb\u003Esymptoms that mimic conditions such as skin allergies\u003C\/b\u003E. Sadly, at this stage, there is no known cure.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cblockquote\u003E“Prognosis is variable depending on the type of lymphoma and the approach to treatment,” says Dr Finlay.\u003C\/blockquote\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“Dogs with indolent lymphoma can enjoy years of disease control. The outcome for dogs with \u003C\/span\u003E\u003Cb style=\"font-family: georgia;\"\u003Ehigh grade lymphoma treated with chemotherapy\u003C\/b\u003E\u003Cspan style=\"font-family: georgia;\"\u003E is typically around 10 to 12 months, however 20 to 30 per cent of dogs will survive two years or more.”\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEikGmy0ABsLQ_jsBRPOUoxeW5y2f0QX6s4d4RRhxHSPqIRmfQkGZ3g4G8CDp4ip_GLQ2UG0N2989sr9cS8cptYSrd20FVt8mJdTskICPKrMkzBeqNV_KztSX0rQWwNGGhFu7rw3Ijr7RucviIN_rJ-m6Y_2jPlbZHC9TV9R9UiLEX2cMRsDxiswG53b\/s1620\/Treating_Canine_Lymphoma_Veterinarian_examining_Australian_Shepherd_lying_on_consultation_table%20-%20Credit%20Freepik.jpg\" style=\"clear: left; float: left; font-size: medium; margin-bottom: 1em; margin-right: 1em; text-align: center;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1080\" data-original-width=\"1620\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEikGmy0ABsLQ_jsBRPOUoxeW5y2f0QX6s4d4RRhxHSPqIRmfQkGZ3g4G8CDp4ip_GLQ2UG0N2989sr9cS8cptYSrd20FVt8mJdTskICPKrMkzBeqNV_KztSX0rQWwNGGhFu7rw3Ijr7RucviIN_rJ-m6Y_2jPlbZHC9TV9R9UiLEX2cMRsDxiswG53b\/s16000\/Treating_Canine_Lymphoma_Veterinarian_examining_Australian_Shepherd_lying_on_consultation_table%20-%20Credit%20Freepik.jpg\" \/\u003E\u003C\/a\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003ETo diagnose lymphoma, the vet usually takes a \u003Cb\u003Esample of the affected lymph node or organ to be analysed\u003C\/b\u003E by a pathologist. If there are any enlarged lymph nodes, the vet may take a fine needle aspirate to look at the cells under the microscope. The tissue may also be taken by a biopsy. These samples are usually then stained to confirm which type of lymphoma is present – B cell or T cell. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgILdLb5RxFdT0VvYCt65spM87AScAOiTA6nu3iwCXTgZOI2xhg_kGJKabXR4oZEbOgbUwuMxexUCVQHKb7_NHp5z2bdn5GDnARBFh57v7eoSJjTy_PpLANkj_9bfbxskW49TI33-cUvFNmMn7lI8hRkHwybBrjksaDeFnweA1bBIMpnjL5RTf9xfp1\/s720\/Animal_Referral_Hospital_Brisbane_Veterinary_Oncologist_Dr_Kathleen_O'Connell.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"720\" data-original-width=\"720\" height=\"320\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEgILdLb5RxFdT0VvYCt65spM87AScAOiTA6nu3iwCXTgZOI2xhg_kGJKabXR4oZEbOgbUwuMxexUCVQHKb7_NHp5z2bdn5GDnARBFh57v7eoSJjTy_PpLANkj_9bfbxskW49TI33-cUvFNmMn7lI8hRkHwybBrjksaDeFnweA1bBIMpnjL5RTf9xfp1\/s320\/Animal_Referral_Hospital_Brisbane_Veterinary_Oncologist_Dr_Kathleen_O'Connell.jpg\" width=\"320\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E“Newer tests that are available to assist with diagnosis include \u003Cb\u003Eflow cytometry\u003C\/b\u003E which can assist with a diagnosis of lymphoma and in certain instances assist with prognosis,” says \u003Cb\u003EDr Kathleen O’Connell\u003C\/b\u003E, specialist vet oncologist at the \u003Ca href=\"https:\/\/arhvets.com.au\/brisbane\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EAnimal Referral Hospital (ARH) Brisbane\u003C\/span\u003E\u003C\/a\u003E, QLD.\u0026nbsp;\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: large;\"\u003E“This test is performed like a fine needle aspirate with cells taken from a lymph node or organ and ran through a machine.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: large;\"\u003EAnother test is called \u003Cb\u003EPARR\u003C\/b\u003E [PCR for Antigen Receptor Rearrangements] which is looking at whether the cells are clones of each other which indicates lymphoma rather than reactive lymphocytes.”\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EDr Finlay says there’s been a \u003Cb\u003Emassive advancement in the understanding of lymphoma\u003C\/b\u003E in recent years. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“In particular, genetic and molecular aberrations, understanding of the tumour microenvironment and the immune landscape,” she says. “This has refined classifications and led to the development of advanced diagnostic tests and revolutionary treatments.” \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana;\"\u003E\u003Cb\u003ENew treatments for lymphoma \u003C\/b\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EOne of these revolutionary treatments is currently being evaluated by biotech company,\u003Cb\u003E\u003Ci\u003E PharmAust\u003C\/i\u003E\u003C\/b\u003E. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EIts newly formulated \u003Cb\u003Eanti-cancer drug Monepantel \u003C\/b\u003E(MPL) is being trialled for dogs with \u003Cb\u003Euntreated B cell lymphoma\u003C\/b\u003E and has already seen success in Phase 1 and Phase 2 clinical trials.\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEj9AYPOSD59eKN_OOU0W8mAAr8jkV29ppPRQQiKlkDXSYk08s_kRkpJp_722CSGrDnvUua6dHp258z8OQJmADNgfN36A9orvINmsftYR9BFJ99G1D-xezefN9fLQRhJnHt5ZH1cmLx_Dw8m1swamHDUJS8Vj0rJ8sh-zKPShNufcGwHe8Xb5pLecVTw\/s2048\/Treating_Canine_Lymphoma_PharmAust_Monepantel_trial_successful_for_Riley_the_Border_Collie.jpg\" style=\"clear: right; float: right; margin-bottom: 1em; margin-left: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"2048\" data-original-width=\"1365\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEj9AYPOSD59eKN_OOU0W8mAAr8jkV29ppPRQQiKlkDXSYk08s_kRkpJp_722CSGrDnvUua6dHp258z8OQJmADNgfN36A9orvINmsftYR9BFJ99G1D-xezefN9fLQRhJnHt5ZH1cmLx_Dw8m1swamHDUJS8Vj0rJ8sh-zKPShNufcGwHe8Xb5pLecVTw\/w266-h400\/Treating_Canine_Lymphoma_PharmAust_Monepantel_trial_successful_for_Riley_the_Border_Collie.jpg\" width=\"266\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“During Phase 2a and Phase 2b trials, Monepantel demonstrated\u0026nbsp;\u003Cb\u003Eeffective anti-cancer activity and minimal side effects\u003C\/b\u003E, which supports continued development into Phase 3 registration trials,” says\u0026nbsp;\u003Cb\u003EDr Kim Agnew\u003C\/b\u003E, Principal Investigator of the trial. “Survival expectations are anticipated to align to a range of single active chemotherapy programs in dogs.”\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cb\u003ETwenty-seven pet dogs have now been treated\u003C\/b\u003E using MPL monotherapy on the trial. Of the 16 pet dogs with optimum blood levels, 13 have achieved stable target lesions and nine of these 16 dogs have achieved stable disease by \u003Ci\u003ERECIST\u003C\/i\u003E (Response Evaluation Criteria in Solid Tumours). \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003EOne canine that took part in the trial, Ryley the \u003Ca href=\"https:\/\/www.australiandoglover.com\/2015\/09\/border-collie.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EBorder Collie\u003C\/span\u003E\u003C\/a\u003E, achieved so much success, she lived for an incredible 191 days after the start of her MPL treatment. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“Our main aim was to hopefully extend her life, but more importantly, maintain her quality of life,” says Sharon, Ryley’s owner. “We are grateful for the extra time we could spend with her.” \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Ctable cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: left; margin-right: 1em; text-align: left;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEiZE4cYSSdFiDWzT4iElBVEwREQCWnekDPWMOpGTwSnQs0A5OvujmlBKA_YXmg0UOywrTdkMO1liBToCbkUx9shtE-3AnOoI7dlREHpYgazLmkMKoEOiSpAwaxbRErQdqWx1XQKYFh0zcVfn81nyK0npnNQ3HGnoSJzA0Gzx8EtWfTWvpAuk8jZJcsX\/s640\/Dr_Kathleen_O'Connell_ARH_Brisbane_with_Ruby_Cavalier_King_Charles_Spaniel.jpg\" style=\"clear: left; margin-bottom: 1em; margin-left: auto; margin-right: auto;\"\u003E\u003Cimg border=\"0\" data-original-height=\"640\" data-original-width=\"480\" height=\"400\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEiZE4cYSSdFiDWzT4iElBVEwREQCWnekDPWMOpGTwSnQs0A5OvujmlBKA_YXmg0UOywrTdkMO1liBToCbkUx9shtE-3AnOoI7dlREHpYgazLmkMKoEOiSpAwaxbRErQdqWx1XQKYFh0zcVfn81nyK0npnNQ3HGnoSJzA0Gzx8EtWfTWvpAuk8jZJcsX\/w300-h400\/Dr_Kathleen_O'Connell_ARH_Brisbane_with_Ruby_Cavalier_King_Charles_Spaniel.jpg\" width=\"300\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Cspan style=\"background-color: white; color: #222222; text-align: start;\"\u003E\u003Ci\u003E\u003Cspan style=\"font-size: medium;\"\u003ERuby Flux \u0026amp; Dr Kathleen O’Connell\u003C\/span\u003E\u003C\/i\u003E\u003C\/span\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003ERuby Flux, the \u003Ca href=\"https:\/\/www.australiandoglover.com\/2015\/10\/cavalier-king-charles-spaniel.html\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003ECavalier King Charles Spaniel\u003C\/span\u003E\u003C\/a\u003E, is currently on Monepantel treatment, and the outcome is looking promising. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“Ruby commenced on the trial in July 2022 with a diagnosis of large cell B cell multicentric lymphoma and she has been going well since,” says Dr O’Connell.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E“She has started another medication, \u003Ci\u003Eprednisolone\u003C\/i\u003E, in August when her disease started to progress, but she is currently very well and loving life.” \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cb\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana;\"\u003EParticipating in the clinical trial \u003C\/span\u003E\u003C\/b\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThe \u003Cb\u003E\u003Ci\u003EMonepantel\u003C\/i\u003E\u003C\/b\u003E trial involves consultations \/ treatments at the nearest trial centre, which currently includes\u003Cb\u003E five sites in Australia\u003C\/b\u003E, one site in New Zealand and one site in the United States. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003E\u003Ci\u003EPerth Vet Specialists\u003C\/i\u003E\u003C\/b\u003E and \u003Cb\u003E\u003Ci\u003EAnimal Referral Hospital Brisbane\u003C\/i\u003E\u003C\/b\u003E are two of the sites in Australia with Dr Findlay and Dr O’Connell heading the trials there.  \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003ETo participate in the Phase 2b trial, dogs can have any stage of lymphoma but must be feeling generally well. Ultimately, the patient will only be given the treatment if they have B cell lymphoma but immunophenotyping (analysis of whether the cancer is a B cell or T cell type) is covered as part of the initial screening.\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThe dog entry criteria for the new clinical trial program are:\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003EAny stage of lymphoma\u003C\/b\u003E (based on physical exam) \u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003ESubstage A (feeling well) \u003C\/b\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003EDogs of any sex and \u003Cb\u003Eat least one year of age \u003C\/b\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003EImmunophenotype can be pending but must be submitted, and needs to be B-cell to confirm enrolment \u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003ENo previous treatment in the previous 8 weeks, including corticosteroids (prednisolone) \u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003ENo other significant concurrent medical problems \u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cb\u003EGood quality of life \u003C\/b\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cspan style=\"background-color: white; color: #555555; font-family: \u0026quot;times new roman\u0026quot;; font-size: large;\"\u003E✔️\u0026nbsp;\u003C\/span\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThe dog should \u003Cb\u003Eweigh more than 11kg \u003C\/b\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EOwners will have to transport their dogs to their respective centre and pay the cost for initial consultation for diagnosis. Once the pet is diagnosed with lymphoma, \u003Cb\u003E\u003Ci\u003EPharmAust\u003C\/i\u003E\u003C\/b\u003E will cover all clinical trial costs, including travel expenses to and from the trial centre as well as post-trial maintenance treatment if both pet owners and vets consider this might be beneficial. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThe tablets will be administered at home and owners will be asked to keep a simple logbook during the trial period. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EFor more information on the \u003Cb\u003EMonepantel anti-cancer drug trial\u003C\/b\u003E, please visit\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Ca href=\"http:\/\/www.pharmaust.com\/petdogtrial\/\" style=\"font-family: georgia;\"\u003E\u003Cspan\u003E\u003Cb\u003E\u003Cspan style=\"color: #2b00fe;\"\u003Ewww.pharmaust.com\/petdogtrial\/\u003C\/span\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/a\u003E \u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEj8wcc7Qqyx5vdqE9TohjPZU0dNknRrubYl3wYg_Ejbwdz8kLXGYKG5VIC0mesQIksKPjtFHVm-a6dbcBCXElGB0ryKv8BWvaKAb3Ww3Io7ilJFRu9P9N9C5QgZAIuoAksg-wRc76bk9GFWjsLzJVS72C4UDulA0FFz_m1gYFpCUHJYdrcJHqPB8HoG\/s1650\/Treating_Canine_Lymphoma_Checking_Dogs_for_Lumps_PharmAust_Infographic_Common_Lymph_Nodes_Targeted_by_Lymphoma.png\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"1162\" data-original-width=\"1650\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEj8wcc7Qqyx5vdqE9TohjPZU0dNknRrubYl3wYg_Ejbwdz8kLXGYKG5VIC0mesQIksKPjtFHVm-a6dbcBCXElGB0ryKv8BWvaKAb3Ww3Io7ilJFRu9P9N9C5QgZAIuoAksg-wRc76bk9GFWjsLzJVS72C4UDulA0FFz_m1gYFpCUHJYdrcJHqPB8HoG\/s16000\/Treating_Canine_Lymphoma_Checking_Dogs_for_Lumps_PharmAust_Infographic_Common_Lymph_Nodes_Targeted_by_Lymphoma.png\" \/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cb\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana;\"\u003EHow to check your dog for lumps \u003Cbr \/\u003E\u003C\/span\u003E\u003C\/b\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-family: georgia;\"\u003EYou should \u003Cb\u003Echeck your dog’s entire body for unusual lumps and bumps on a regular basis\u003C\/b\u003E.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan style=\"font-family: georgia;\"\u003EThey may be a sign of canine cancer. Here’s how you can safely check their body in four easy steps:\u003C\/span\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cul style=\"text-align: left;\"\u003E\u003Cli\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: large;\"\u003EAlways praise your dog for being tolerant of being touched all over and offer rewards (food or praise) throughout the process.\u003C\/span\u003E\u003C\/span\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cul style=\"text-align: left;\"\u003E\u003Cli\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: large;\"\u003EUsing gentle pressure, start with feeling your dog’s head and run your hands around their face, paying particular attention to under the jaw and around the neck.\u003C\/span\u003E\u003C\/span\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cul style=\"text-align: left;\"\u003E\u003Cli\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: large;\"\u003EThen, move your hands down the chest, over the arms and feel under the armpits. Run your hands across the underside of the tummy paying particular attention to the mammary area in female dogs.\u003C\/span\u003E\u003C\/span\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cul style=\"text-align: left;\"\u003E\u003Cli\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: large;\"\u003EWhile your dog is standing, look under the tail and check around the back passage, then run your hands down each of their legs. \u003C\/span\u003E\u003C\/span\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-size: large;\"\u003EMake sure to visit your vet if you do find any unusual or new lumps and ulcerations. \u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cspan\u003EWritten by \u003C\/span\u003E\u003Cb\u003EKylie Baracz\u003C\/b\u003E\u003Cspan\u003E, \u003Cb\u003EOctober\u003C\/b\u003E\u003C\/span\u003E\u003Cb\u003E\u0026nbsp;2022\u003C\/b\u003E\u003Cspan\u003E for \u003C\/span\u003E\u003Cb\u003E\u003Ci\u003EAustralian Dog Lover\u003C\/i\u003E\u003C\/b\u003E\u003Cspan\u003E (all rights reserved).\u003C\/span\u003E\u003C\/span\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cb\u003E\u003Cu\u003EAbout Kylie Baracz \u003C\/u\u003E\u003C\/b\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Ctable cellpadding=\"0\" cellspacing=\"0\" class=\"tr-caption-container\" style=\"float: left; margin-right: 1em; text-align: left;\"\u003E\u003Ctbody\u003E\u003Ctr\u003E\u003Ctd style=\"text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhxZ6QJt4c2uy7QzHJi48AKyf7AoXVJlgzZ5ZCXhO2W_l2uKhJGY0zo-RPUs-WWWcFN77i-1Ns_QpKlUe16tyf5l3orf5MTfXpukRFRvencP9qIczO6xdSzRDp_i_iUGc5FozHzNnJgPddurz9joIEZxGBq-pqA59ZXlAE_bpsRskapgDs6hdhny24K\/s488\/Kylie_Baracz_Copywriter_Content_by_Kylie_bio_photo.jpg\" style=\"clear: left; margin-bottom: 1em; margin-left: auto; margin-right: auto;\"\u003E\u003Cimg border=\"0\" data-original-height=\"488\" data-original-width=\"488\" height=\"320\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEhxZ6QJt4c2uy7QzHJi48AKyf7AoXVJlgzZ5ZCXhO2W_l2uKhJGY0zo-RPUs-WWWcFN77i-1Ns_QpKlUe16tyf5l3orf5MTfXpukRFRvencP9qIczO6xdSzRDp_i_iUGc5FozHzNnJgPddurz9joIEZxGBq-pqA59ZXlAE_bpsRskapgDs6hdhny24K\/w320-h320\/Kylie_Baracz_Copywriter_Content_by_Kylie_bio_photo.jpg\" width=\"320\" \/\u003E\u003C\/a\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003Ctr\u003E\u003Ctd class=\"tr-caption\" style=\"text-align: center;\"\u003E\u003Cspan face=\"Arial, Helvetica, sans-serif\" style=\"background-color: white; color: #222222; font-size: small; text-align: start;\"\u003E\u003Ci\u003EPhoto: Felicity Harris Photography\u003C\/i\u003E\u003C\/span\u003E\u003C\/td\u003E\u003C\/tr\u003E\u003C\/tbody\u003E\u003C\/table\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003EKylie is a freelance writer, editor and content creator with over 11 years’ experience in the media industry.\u0026nbsp;\u003C\/div\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003EAs a former\u003Ci\u003E Dogs Life \u003C\/i\u003Emagazine editor, Kylie has a passion for writing for the pet industry and has worked with many pet brands including \u003Cb\u003E\u003Ci\u003EAPDTA\u003C\/i\u003E \u003C\/b\u003Eand \u003Ci\u003E\u003Cb\u003EPPGA\u003C\/b\u003E\u003C\/i\u003E, \u003Ci\u003E\u003Cb\u003EPharmAust\u003C\/b\u003E\u003C\/i\u003E and \u003Ci\u003E\u003Cb\u003EBest Pets Gift Card\u003C\/b\u003E\u003C\/i\u003E.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003EYou can find her on Instagram \u003Ca href=\"https:\/\/www.instagram.com\/contentbykylie\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003E@contentbykylie\u003C\/span\u003E\u003C\/a\u003E or at \u003Ca href=\"https:\/\/contentbykylie.com.au\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: red;\"\u003E\u003Cb\u003Econtentbykylie.com.au\u003C\/b\u003E\u003C\/span\u003E\u003C\/a\u003E\u0026nbsp;\u003Cbr \/\u003E\u003Cb\u003E\u003Cu\u003E\u003Cbr \/\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb style=\"font-family: georgia; font-size: large;\"\u003E\u003Cu\u003E\u003Cbr \/\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb\u003E\u003Cu\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb\u003E\u003Cu\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb\u003E\u003Cu\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb\u003E\u003Cu\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cb\u003E\u003Cu\u003E\u003Cspan style=\"font-family: georgia; font-size: medium;\"\u003EAbout PharmAust\u003C\/span\u003E\u003C\/u\u003E\u003C\/b\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cbr \/\u003E\u003Cdiv class=\"separator\" style=\"clear: both; text-align: center;\"\u003E\u003Ca href=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjePIbISF71qDOauxGEuauo48Oh-_z-26N4xVXqwHvFusvxBO4Ot3rMgzYLT25KE7hir6cvcTpkOZMfNWNvxVd8rSDotWxmtaWmlB0_nBEM7iHvQDLE3w8-ZV_QG9jB5Ms6DlzbaKdCa5Gau7sMDN38mQXQkm-00C3hQdErxCo48kEZOpEyUvnCpSZg\/s200\/PharmAust_Logo_Canine_Lymphoma_Monepantel_Dog_Cancer_Trials.jpg\" style=\"clear: left; float: left; margin-bottom: 1em; margin-right: 1em;\"\u003E\u003Cimg border=\"0\" data-original-height=\"53\" data-original-width=\"200\" height=\"85\" src=\"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjePIbISF71qDOauxGEuauo48Oh-_z-26N4xVXqwHvFusvxBO4Ot3rMgzYLT25KE7hir6cvcTpkOZMfNWNvxVd8rSDotWxmtaWmlB0_nBEM7iHvQDLE3w8-ZV_QG9jB5Ms6DlzbaKdCa5Gau7sMDN38mQXQkm-00C3hQdErxCo48kEZOpEyUvnCpSZg\/w320-h85\/PharmAust_Logo_Canine_Lymphoma_Monepantel_Dog_Cancer_Trials.jpg\" width=\"320\" \/\u003E\u003C\/a\u003E\u003C\/div\u003EPAA is a clinical-stage company developing targeted cancer therapeutics for both humans and animals. The company specialises in repurposing marketed drugs lowering the risks and costs of development. \u003Cbr \/\u003E\u003Cbr \/\u003EPAA’s lead drug candidate is monepantel (MPL), a novel, potent and safe inhibitor of the mTOR pathway - a key driver of cancer.  PAA is uniquely positioned to commercialise MPL for treatment of human and veterinary cancers as it advances the drug into Phase 2b clinical trial.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cspan style=\"font-size: medium;\"\u003ETo discover more, visit \u003Ca href=\"https:\/\/www.pharmaust.com\/\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: red;\"\u003E\u003Cb\u003Ewww.pharmaust.com\u003C\/b\u003E\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #3d85c6; font-family: verdana; font-size: large;\"\u003E\u003Cb\u003ERelated Topics:\u003C\/b\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cbr \/\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #2b00fe; font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2022\/08\/update-on-pharmaust-canine-cancer-trials.html\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EUpdate on PharmAust Canine Cancer Trials\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #2b00fe; font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2021\/10\/call-for-dogs-to-help-continued.html\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003ECall for Dogs to Help Continued Evaluation of Exciting New Anti-cancer Drug\u003C\/span\u003E\u003C\/a\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"font-family: georgia; font-size: large;\"\u003E\u003Cbr \/\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cspan style=\"color: #2b00fe; font-family: georgia; font-size: large;\"\u003E\u003Ca href=\"https:\/\/www.australiandoglover.com\/2018\/01\/evaluating-lumps-and-bumps-in-dogs.html\" rel=\"nofollow\" target=\"_blank\"\u003E\u003Cspan style=\"color: #2b00fe;\"\u003EEvaluating Lumps and Bumps in Dogs\u003C\/span\u003E\u003C\/a\u003E\u0026nbsp;\u003C\/span\u003E\u003C\/div\u003E"},"link":[{"rel":"replies","type":"application/atom+xml","href":"https:\/\/www.australiandoglover.com\/feeds\/5735331694114771334\/comments\/default","title":"Post Comments"},{"rel":"replies","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2022\/10\/treating-canine-lymphoma-why-you-should.html#comment-form","title":"0 Comments"},{"rel":"edit","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/5735331694114771334"},{"rel":"self","type":"application/atom+xml","href":"https:\/\/www.blogger.com\/feeds\/2020204049726645298\/posts\/default\/5735331694114771334"},{"rel":"alternate","type":"text/html","href":"https:\/\/www.australiandoglover.com\/2022\/10\/treating-canine-lymphoma-why-you-should.html","title":"Treating Canine Lymphoma | Why you should check your dog for lumps"}],"author":[{"name":{"$t":"Australian Dog Lover"},"uri":{"$t":"http:\/\/www.blogger.com\/profile\/00400760178634828393"},"email":{"$t":"noreply@blogger.com"},"gd$image":{"rel":"http://schemas.google.com/g/2005#thumbnail","width":"16","height":"16","src":"https:\/\/img1.blogblog.com\/img\/b16-rounded.gif"}}],"media$thumbnail":{"xmlns$media":"http://search.yahoo.com/mrss/","url":"https:\/\/blogger.googleusercontent.com\/img\/b\/R29vZ2xl\/AVvXsEjcVpKWEC_IfPzdBfJSwI8fvSS3JUrZRAa19c9bgTcdkbKsViUUL8kGunp0JwAQQJJCTJ5CQJdUKpN23wk28mW-ePZ3GDwIWDo5hv18WIrRbhWBXb-rpHHQQdW_ZYrelzS294zTDO-dO3W8BCrVzojaLDREWVbQrEZI5J3HoxD13TOrCu5MSp5IpUU2\/s72-c\/Treating_Canine_Lymphoma_Vet_Checks_Lymph_Nodes_on_a_Terrier.jpg","height":"72","width":"72"},"thr$total":{"$t":"0"}}]}});